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MIRCen, SHFJ, Neurospin - CEA Paris-Saclay 

 

 

MIRCen, NeuroSpin and Service Hospitalier Frédéric Joliot (SHFJ) are preclinical research centers created by CEA Paris-Saclay. Focused on neuroimaging, they host state-of-the-art instrumental platforms and research teams with complementary expertise. The research within these three centers capitalizes on « in vivo » brain imaging technological and methodological developments to translate the research into clinical level, and more specifically for the creation of new tools improving the diagnosis and / or the evaluation of innovative therapies.

Installed on 30,000 m² of platforms, MIRCen, SHFJ and Neurospin bring together nearly 500 researchers, clinicians, doctors, engineers, technicians, doctoral students and post-docs from CEA Paris-Saclay, Inserm, CNRS, AP-HP and INRIA.

 

Molecular Imaging Research Center (MIRCen)

MIRCen is a preclinical research center based at the CEA center in Fontenay aux Roses, which brings together about a hundred or so researchers, engineers, technicians, clinicians and students from CEA, Inserm and CNRS.

 

 

MIRCen is dedicated to the development of animal models relevant to human neurological diseases  and to preclinical trials of gene, cell and drug therapies for the treatment of neurodegenerative diseases (mainly for Alzheimer's, Parkinson's and Huntington's diseases), by relying in particular on the expertise of the Laboratory of Neurodegenerative Diseases UMR 9199, CEA / CNRS / Université Paris-Saclay.

 

In addition, MIRCEn provides 16 platforms, including PET and MRI imaging, NMR spectroscopy, neurosurgery rooms, equipment dedicated to behavioral studies, as well as biochemistry and molecular biology laboratories. Most of these platforms operate in microbiological safety level L2 and L3. This state-of-the-art equipment is used to assess neurodegeneration in animal models (and longer term in patients) and to test innovative therapeutic strategies.

 

 

MIRCen thus has the main platforms and expertise to undertake a translational research approach aimed at proposing, characterizing and measuring in animals (rodents and non-human primates) then in humans, the therapeutic efficacy of different therapeutic approaches of cellular, gene and / or drug as well as new interventional surgery treatments.

Recently and  within an agreement between MIRCen and the Institute of Vision (IDV), a preclinical platform in ophthalmology dedicated to non-human primates has been set up and made available for collaborative studies (More information).

 

> Learn more about MIRCen
   

Service Hospitalier Frédéric Joliot (SHFJ)

SHFJ is a preclinical and clinical research center specialized in molecular and functional imaging, associated to a clinical nuclear medicine department. A pioneer in Europe in the field of PET molecular imaging (PET-MRI clinical hybrid imager), especially for neurotransmission imaging and quantification of membrane receptors, SHFJ is based on the Orsay Hospital site  until it moves to the Saclay plateau.

The SHFJ provides a medical service mission and a research and development mission, which are mainly in the three following disciplines: oncology, neurology and pharmacology. This research aims to create new imaging tools to improve the diagnosis and evaluation of innovative therapies.

> Learn more about SHFJ
 

NeuroSpin

NeuroSpin is a research center for innovation in brain imaging located at the CEA Center in Saclay, in Gif sur Yvette. The expertise of its physicists, mathematicians and doctors located in the NeuroSpin’s four research units and its 11,000 m2 of platforms, enable it to carry out preclinical studies of imaging and biomedical research. Equipped with very high resolution imagers (including 1 MRI scanner at 17.2 Tesla, the only one in the world), NeuroSpin develops and uses tools and models to better analyze the developing or functioning human brain, as well as the pathologies that affect it (neurological and psychiatric diseases). 

> Learn more about NeuroSpin