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Pour chaque pathologie (Alzheimer, Parkinson, Huntington et sclérose en plaques), NeurATRIS dispose de plateformes de haute-technologie et de modèles complémentaires (cellules, animaux) permettant de cribler, caractériser, évaluer et valider jusqu’au patient (Phase II) vos développements les plus prometteurs.

         
Alzheimer Parkinson Huntington multiple sclerosis - Neurons / astrocytes / microglia:
* treated with toxins
*infected with viral vectors
(LV / AAV)
- ESC or iPS
- treated with neurotoxins
- infected with viral vectors (LV / AAV)
-Transgenic animals
- treated with neurotoxins
- infected with viral vectors (LV / AAV)
- Characterized cohorts of patients
- Biobanks
Platforms

NeuroImaging: PET / MRI / PET-CT / PET-MRI / SPECT, etc.

 

Cognition and Behavior: Memory, language, motivation, movement, muscular strength, etc.

 

Therapeutic approches: gene transfer, celle graft, aptamers, neurosurgery, etc.

 

Electrophysiology: Path recording, MEG and EEG, recording from cell culture, brain slice, etc.

 

Complementary expertise: ex vivo imaging, HTS, applied Immunology, hugh-throughput real time PCR, biochemistry and proteomics, pharmacokinetics, etc.

 

Biosafety environnement: BSL1, 2, 3 for neurosurgery, imaging, histopathology, behavior, etc.