A controlled opening device of the blood-brain barrier by combined use of MRI and ultrasound is now installed in MirCen This equipment has been funded by FEDER.
Access circulating molecules to the brain is strongly limited by the blood-brain barrier (BBB). This represents a major obstacle to the development of new drugs for central nervous system diseases, particularly biotherapy
For 15 years , ultrasound has been proposed as an effective solution to permeabilize temporarily and locally this barrier and allow to issue large amounts of therapeutic agents where they need to act.