I-STEM's platforms are dedicated to the production, analysis and high-throughput screening of pluripotent stem cell derivatives, which are essential for the study of monogenic diseases.
They are structured around 5 axes:
AUTOMATED BIOPRODUCTION :
This platform enables large-scale cell production while guaranteeing strict quality control, through the standardisation and automation of the culture and differentiation processes of human pluripotent stem cells.
)HIGH AND MEDIUM THROUGHPUT PHARMACOLOGICAL COMPOUND SCREENING (HTS):
Equipped with high-performance robots, this platform enables the identification of potential drug molecules through the performance of high and medium-throughput screening.
) CELLULAR IMAGERY :
This platform allows the acquisition of microscopic images of tissues or cells necessary for the visualisation, control, illustration and analysis of cell lines or tissues.
) CELL BIOLOGY :
This platform has the expertise and equipment necessary for the quality control of human pluripotent cells and their derivatives as well as for the optimisation of the culture protocols of these cells and their transposition from "research grade" protocols to "clinical grade" processes.
) GENOMIC ANALYSIS (NGS) :
This platform offers high-throughput genome and/or transcriptome sequencing services as well as scientific and technical support adapted to each project.
) BIOBANK :
This platform has a large number of cell types of interest, relevant pathological models of various monogenic diseases.