As part of the Health Innovation Plan France 2030 call for projects, NeurATRIS has been selected to receive funding of €4.8 million, with the aim of modernizing its technological offering and accelerating its technological developments in terms of preclinical imaging and biomarker and biotherapy screening.

A STRATEGIC SUPPORT FOR FRENCH RESEARCH

As part of the France 2030 Health Innovation Plan, the government has decided to renew a large-scale investment plan for the biology-health sector, aimed at funding the rejuvenation and modernization of the technological and service offerings of the National Infrastructures for Biology and Health (INBS). This initiative seeks to maintain their competitiveness and better align their services with the needs of the relevant scientific communities.

A budget of 80 million euros has been allocated to the INBS to ensure their sustainability. NeurATRIS is among the seventeen infrastructures selected, underscoring the vital role of the infrastructure in the French landscape of translational neurosciences.

MODERNIZATION OF NEURATRIS EQUIPMENT

NeurATRIS offers a wide range of tools covering the entire continuum of translational neuroscience research, from molecular and cellular biology to studies on animal models and humans. However, with recent technological advancements, some essential equipment has become obsolete and needs to be renewed.

     * PRECLINICAL IN VIVO IMAGING:

     - The preclinical tomography scanners at the CEA-MIRCen PET platform, used for imaging biomarker studies, will be replaced by next-generation models that are more sensitive and offer higher resolution. This upgrade will facilitate advanced studies on rodent and non-human primate models.

     * IN VITRO SCREENING OF BIOTHERAPIES:

- The imaging platform at the Brain Institute (ICM.Quant) will be equipped with a high-throughput imaging system to study complex models, such as organotypic slices or organoids derived from human iPS cells.

- The animal histology platform at UMR 703 PAnTher (APEX) will acquire a multiphoton microscope for multi-scale phenotyping of tissues and cells.

- The imaging platform at Neuro-Bicêtre will replace its aging transmission electron microscope (TEM) and pair it with new correlative microscopy approaches (CLEM).

DEVELOPMENT OF NEW SCREENING AND ANALYSIS CAPABILITIES

In order to maintain NeurATRIS platforms at the highest scientific and technical level, new capabilities will also be developed.

     * IN VITRO SCREENING OF SMALL MOLECULES:

 - Leveraging the expertise of the histology (Histomics), genomics (iGenseq), and data analysis (DAC) platforms, the ICM will develop a new large-scale multi-Omics spatial histology platform to support the discovery of new therapeutic targets and biomarkers.

- The APEX platform at UMR 703 PAnTher will acquire a spinning-disk microscope coupled with a DeepSIM super-resolution module, enabling the acquisition of super-resolved data from thick, non-cleared samples.

     * IN VITRO SCREENING OF BIOTHERAPIES:

     - The bioinformatics platform at Henri Mondor Hospital will acquire new bioinformatics servers, essential for "machine learning" studies developed for the early diagnosis of patients with Huntington's disease or Parkinson's disease (voice analysis).

     - The proteomics platform at Henri Mondor Hospital will acquire protein quantification equipment for high-throughput analysis of biological samples from patients.

     - The DHIM platform of the NeuroDiderot Unit 1141 will acquire an ultra-resolution multiplexed imaging system, enabling complex analyses that require the detection of multiple biomarkers in biological samples.

It is worth noting that NeuraTRIS has also received a grant included in the State budget, ensuring the necessary funding for its operation in the coming years.

France Parkinson is funding 4 to 6 travel grants for the 5th Gordon Research Conference on Parkinson's Disease, which takes place from 8 to 13 June 2025 in Waterville Valley, New Hampshire, USA. The travel grants are intended for PhD or post-doctoc researchers, working on Parkinson's disease in a laboratory in France.

The Gordon Research Conference (GRC) on Parkinson's disease brings together scientists from many disciplines to discuss the most important questions in the basic science of Parkinson's disease, including the mechanisms of pathogenesis and pathophysiology, and how this might influence therapeutics.

As with the other GRCs, there will be plenty of time for discussion and informal networking opportunities between students, postdocs and group leaders. It is therefore a unique opportunity for young doctoral and post-doctoral researchers to present their work, discuss new methods, innovative ideas and pre-published data, and develop collaborative relationships with their peers. Experienced mentors and moderators will facilitate active participation in scientific discussions to enable all participants to be engaged actors rather than spectators.

The selection committee will choose a total of 150 abstracts. France Parkinson will support the travel and registration to the congress of the first 5 candidates meeting the following criteria:

          1. Work in a research centre in France

          2. Be a PhD student or post-doctoral fellow

          3. Have your abstract selected by the GRC committee.

If you are interested in taking part, please consult our current programme and send your application to https://www.grc.org/parkinson-s-disease-conference/2025/.

Oral presentations (particularly from junior researchers) will be selected from the abstracts submitted.

In order to promote the careers of doctoral and post-doctoral students, this meeting is associated with a Gordon Research Seminar (GRS), to be held on 7 and 8 June 2025. The GRS allows trainees to meet and learn more about the field before the GRC begins. View the agenda and register for the GRS here:https://www.grc.org/parkinson-s-disease-grs-conference/2025/ .

Other speakers (students and postdocs) will be selected from the abstracts submitted.

REGISTER NOW PLACES ARE LIMITED!

Join us on October 14, 2024, for the NeurATRIS' Annual General Assembly !

Location : Maison des Polytechniciens, Paris

This year, we offer an overview of the latest advances in translational neuroscience, focusing on neurodevelopmental diseases, multiple sclerosis and Alzheimer’s Parkinson’s and Huntington’s diseases.

Highlights of the day:
      - Review of last year’s achievements
      - Presentation of future perspectives for the infrastructure
      - Presentation of initiatives to promote translational neuroscience research as well as the training of young scientists.

More information and the detailed program.
 

Registration is free but mandatory, and opens on Monday, August 26, 2024.

The NeurATRIS Translational Neuroscience Days (TND2024) were held on May 24 and 25, 2024 at the Domaine Ker Juliette in Pornichet, France, as an annual meeting of the neuroscience ecosystem for academic and private players. Co-organized this year with INBS France-BioImaging (FBI) and France Life Imaging (FLI), this 5th edition focused on multi-scale imaging for translational neuroscience research.

DAY 1 :

Day 1 began with a plenary session on “Imaging as a tool for studying molecular and cellular processes”. Participants then attended a round-table discussion on “Data sharing and tools in neuroimaging: where do we stand and where are we going?” moderated and introduced by Michel Dojat (GIN, Inserm U1216 Statify et Inria). 

In the early afternoon, 11 students competed for the NeurATRIS “Next Generation Challenge” prize, presenting their research results in the form of posters. The NeurATRIS prize for the best scientific poster was awarded to not one, but two students who tied, namely Tiffany Bourgeton (UMR703 PAnTher, INRAE/ Oniris) and Victor Valcarcel (CNRS UMR 7221, MNHN).  The second plenary session dealt with “Imaging as a tool for analyzing cerebral and metabolic activity”. On this occasion, Fawzi Boumezbeur from CEA-NeuroSpin spoke about recent brain images obtained with the 11.7T Iseult MRI, a world first. 

This first day ended in a convivial atmosphere with a social event hosted by the improv troupe La LINA.

DAY 2:

The second and final day of the Journées des Neurosciences Translationnelles began with a special lecture by Professor Lehericy Stephane, Institut du Cerveau - Paris Brain Institute, Head of Neuroradiology at Hôpital Pitié-Salpêtrière on “Imaging in translational neuroscience around Parkinson's disease”.  This was followed by a third and final plenary session on “Imaging as a screening tool”.

Many thanks to all participants and speakers, not forgetting our partners and sponsors for supporting our event.

NeurATRIS is co-organizing with France Life Imaging (FLI) and France Bio-Imaging (FBI), the 5^th edition of its Translational Neuroscience Days (TND), on May 24 and 25, 2024 at Domaine Ker Juliette in Pornichet.

The event will take place over the full day of Friday May 24 and the morning of Saturday May 25, and will focus on multi-scale imaging for translational neuroscience research.

Objectives: (i) Present the latest scientific advances (plenary sessions); (ii) Debate a topical issue (round table); (iii) Promote the next generation by offering them the opportunity to present their work in the form of a poster ( Next Generation Challenge prize).

TND enables strong interactions between academic and private players in the field of neuroscience, with a strong focus on young researchers.

Language: French

The pre-programme and registration details will be available soon.

In 2023, NeurATRIS research generated 118 publications in peer-reviewed journals. Many thanks to all our teams and collaborators!

• Abjean, Laurene, Lucile Ben Haim, Miriam Riquelme-Perez, Pauline Gipchtein, Céline Derbois, Marie-Ange Palomares, Fanny Petit, et al. « Reactive Astrocytes Promote Proteostasis in Huntington’s Disease through the JAK2-STAT3 Pathway ». Brain: A Journal of Neurology 146, n^o 1 (5 janvier 2023): 149‑66. https://doi.org/10.1093/brain/awac068.
• Al-Obaidi, Hala, Zainab Khidhair, Feras Jirjees, Muna Barakat, Husam AlSalamat, Zelal Kharaba, Yassen Alfoteih, et al. « Factors Associated with Knowledge and Awareness of Stroke in the Iraqi Population: A Cross-Sectional Study ». Frontiers in Neurology 14 (2023): 1144481. https://doi.org/10.3389/fneur.2023.1144481.
• Andersen, Mads, Hannah Brogård Andersen, Ted Carl Kejlberg Andelius, Lærke Hjøllund Hansen, Regitze Pinnerup, Mette Bjerre, Steffen Ringgaard, et al. « No Neuroprotective Effect of Therapeutic Hypothermia Following Lipopolysaccharide-Sensitized Hypoxia-Ischemia: A Newborn Piglet Study ». Frontiers in Pediatrics 11 (2023): 1268237. https://doi.org/10.3389/fped.2023.1268237.
• Augustin, Sebastien, Marion Lam, Sophie Lavalette, Anna Verschueren, Frédéric Blond, Valérie Forster, Lauriane Przegralek, et al. « Melanophages Give Rise to Hyperreflective Foci in AMD, a Disease-Progression Marker ». Journal of Neuroinflammation 20, n^o 1 (8 février 2023): 28. https://doi.org/10.1186/s12974-023-02699-9.
• Berriat, Félix, Christian S. Lobsiger, et Séverine Boillée. « The Contribution of the Peripheral Immune System to Neurodegeneration ». Nature Neuroscience 26, n^o 6 (juin 2023): 942‑54. https://doi.org/10.1038/s41593-023-01323-6.
• Bertho, Annaig, Lorea Iturri, Elise Brisebard, Marjorie Juchaux, Cristèle Gilbert, Ramon Ortiz, Catherine Sebrie, et al. « Evaluation of the Role of the Immune System Response After Minibeam Radiation Therapy ». International Journal of Radiation Oncology, Biology, Physics 115, n^o 2 (1 février 2023): 426‑39. https://doi.org/10.1016/j.ijrobp.2022.08.011.
• Bizot, Flavien, Abdallah Fayssoil, Cécile Gastaldi, Tabitha Irawan, Xaysongkhame Phongsavanh, Arnaud Mansart, Thomas Tensorer, et al. « Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model ». Cells 12, n^o 5 (23 février 2023): 702. https://doi.org/10.3390/cells12050702.
• Boccazzi, Marta, Giulia Macchiarulo, Sophie Lebon, Justyna Janowska, Tifenn Le Charpentier, Valérie Faivre, Jennifer Hua, et al. « G Protein-Coupled Receptor 17 Is Regulated by WNT Pathway during Oligodendrocyte Precursor Cell Differentiation ». Neurobiology of Disease 187 (15 octobre 2023): 106315. https://doi.org/10.1016/j.nbd.2023.106315.
• Bokobza, Cindy, Alice Jacquens, David Guenoun, Blandine Bianco, Anne Galland, Maxime Pispisa, Alexandra Cruz, et al. « Targeting the Brain 5-HT7 Receptor to Prevent Hypomyelination in a Rodent Model of Perinatal White Matter Injuries ». Journal of Neural Transmission (Vienna, Austria: 1996) 130, n^o 3 (mars 2023): 281‑97. https://doi.org/10.1007/s00702-022-02556-8.
• Boluda, Susana, Karima Mokhtari, Bruno Mégarbane, Djillali Annane, Bertrand Mathon, Albert Cao, Clovis Adam, et al. « Golgi Localization of SARS-CoV-2 Spike Protein and Interaction with Furin in Cerebral COVID-19 Microangiopathy: A Clue to the Central Nervous System Involvement? » Free Neuropathology 4 (janvier 2023): 4‑1. https://doi.org/10.17879/freeneuropathology-2023-4584.
• Bottani, Simona, Ninon Burgos, Aurélien Maire, Dario Saracino, Sebastian Ströer, Didier Dormont, Olivier Colliot, Alzheimer’s Disease Neuroimaging Initiative, et APPRIMAGE Study Group. « Evaluation of MRI-Based Machine Learning Approaches for Computer-Aided Diagnosis of Dementia in a Clinical Data Warehouse ». Medical Image Analysis 89 (octobre 2023): 102903. https://doi.org/10.1016/j.media.2023.102903.
• Bousset, Luc, Ania Alik, Ana Arteni, Anja Böckmann, Beat H. Meier, et Ronald Melki. « α-Synuclein Fibril, Ribbon and Fibril-91 Amyloid Polymorphs Generation for Structural Studies ». Methods in Molecular Biology (Clifton, N.J.) 2551 (2023): 345‑55. https://doi.org/10.1007/978-1-0716-2597-2_23.
• Boutros, Celina F., Walaa Khazaal, Maram Taliani, Najwane Said Sadier, Pascale Salameh, et Hassan Hosseini. « Factors Associated with Cognitive Impairment at 3, 6, and 12 Months after the First Stroke among Lebanese Survivors ». Brain and Behavior 13, n^o 1 (janvier 2023): e2837. https://doi.org/10.1002/brb3.2837.
• Butruille, L., P. Jubin, E. Martin, M. S. Aigrot, M. Lhomme, J. B. Fini, B. Demeneix, et al. « Deleterious Functional Consequences of Perfluoroalkyl Substances Accumulation into the Myelin Sheath ». Environment International 180 (octobre 2023): 108211. https://doi.org/10.1016/j.envint.2023.108211.
• Casse, Fanny, Thomas Courtin, Christelle Tesson, Mélanie Ferrien, Sandrine Noël, Anne-Laure Fauret-Amsellem, Thomas Gareau, et al. « Detection of ATXN2 Expansions in an Exome Dataset: An Underdiagnosed Cause of Parkinsonism ». Movement Disorders Clinical Practice 10, n^o 4 (avril 2023): 664‑69. https://doi.org/10.1002/mdc3.13699.
• Castanha, Nanci, Sylvain Challois, David Grenier, Patricia Le-Bail, Laurence Dubreil, et Tiphaine Lucas. « Multiphoton Microscopy Is a Nondestructive Label-Free Approach to Investigate the 3D Structure of Gas Cell Walls in Bread Dough ». Scientific Reports 13, n^o 1 (26 août 2023): 13971. https://doi.org/10.1038/s41598-023-39797-w.
• Célestine, Marina, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, et Marc Dhenain. « Long Term Worsening of Amyloid Pathology, Cerebral Function, and Cognition after a Single Inoculation of Beta-Amyloid Seeds with Osaka Mutation ». Acta Neuropathologica Communications 11, n^o 1 (22 avril 2023): 66. https://doi.org/10.1186/s40478-023-01559-0.
• Ceyzériat, Kelly, Alekos Nicolaides, Quentin Amossé, Christine Fossey, Thomas Cailly, Frédéric Fabis, Valentina Garibotto, Carole Escartin, Benjamin B. Tournier, et Philippe Millet. « Reactive Astrocytes Mediate TSPO Overexpression in Response to Sustained CNTF Exposure in the Rat Striatum ». Molecular Brain 16, n^o 1 (5 juillet 2023): 57. https://doi.org/10.1186/s13041-023-01041-x.
• Chen, Charles D., Austin McCullough, Brian Gordon, Nelly Joseph-Mathurin, Shaney Flores, Nicole S. McKay, Diana A. Hobbs, et al. « Longitudinal Head-to-Head Comparison of 11C-PiB and 18F-Florbetapir PET in a Phase 2/3 Clinical Trial of Anti-Amyloid-β Monoclonal Antibodies in Dominantly Inherited Alzheimer’s Disease ». European Journal of Nuclear Medicine and Molecular Imaging 50, n^o 9 (juillet 2023): 2669‑82. https://doi.org/10.1007/s00259-023-06209-0.
• Chougar, Lydia, François-Xavier Lejeune, Johann Faouzi, Benjamin Morino, Alice Faucher, Nadine Hoyek, David Grabli, et al. « Comparison of Mean Diffusivity, R2* Relaxation Rate and Morphometric Biomarkers for the Clinical Differentiation of Parkinsonism ». Parkinsonism & Related Disorders 108 (mars 2023): 105287. https://doi.org/10.1016/j.parkreldis.2023.105287.
• Courte, Josquin, Ngoc Anh Le, Teng Pan, Luc Bousset, Ronald Melki, Catherine Villard, et Jean-Michel Peyrin. « Synapses Do Not Facilitate Prion-like Transfer of Alpha-Synuclein: A Quantitative Study in Reconstructed Unidirectional Neural Networks ». Cellular and Molecular Life Sciences: CMLS 80, n^o 10 (9 septembre 2023): 284. https://doi.org/10.1007/s00018-023-04915-4.
• Dahham, Jalal, Mickaël Hiligsmann, Ingrid Kremer, Samia J. Khoury, Hala Darwish, Hassan Hosseini, Silvia Evers, et Rana Rizk. « The Societal Costs of Multiple Sclerosis in Lebanon: A Cross-Sectional Study ». Expert Review of Pharmacoeconomics & Outcomes Research 23, n^o 4 (avril 2023): 419‑30. https://doi.org/10.1080/14737167.2023.2184802.
• Daly, Timothy, et Stéphane Epelbaum. « The Accelerated Approval of Aducanumab Invites a Rethink of the Current Model of Drug Development for Alzheimer’s Disease ». AJOB Neuroscience 14, n^o 3 (2023): 332‑35. https://doi.org/10.1080/21507740.2022.2048721.
• De Pace, Raffaella, Reza Maroofian, Adeline Paimboeuf, Mina Zamani, Maha S. Zaki, Saeid Sadeghian, Reza Azizimalamiri, et al. « Biallelic BORCS8 Variants Cause an Infantile-Onset Neurodegenerative Disorder with Altered Lysosome Dynamics ». Brain: A Journal of Neurology, 21 décembre 2023, awad427. https://doi.org/10.1093/brain/awad427.
• Delabar, Jean M., Julien Lagarde, Marta Fructuoso, Ammara Mohammad, Michel Bottlaender, Eric Doran, Ira Lott, et al. « Increased Plasma DYRK1A with Aging May Protect against Neurodegenerative Diseases ». Translational Psychiatry 13, n^o 1 (4 avril 2023): 111. https://doi.org/10.1038/s41398-023-02419-0.
• Denis, Hélèna L., Melanie Alpaugh, Claudia P. Alvarez, Alexis Fenyi, Roger A. Barker, Sylvain Chouinard, Cheryl H. Arrowsmith, et al. « Detection of Antibodies against the Huntingtin Protein in Human Plasma ». Cellular and Molecular Life Sciences: CMLS 80, n^o 2 (18 janvier 2023): 45. https://doi.org/10.1007/s00018-023-04687-x.
• Dodet, P. « REM Behavior Disorder: When Parkinson’s Disease Meets Morpheus ». Revue Neurologique 179, n^o 7 (octobre 2023): 667‑74. https://doi.org/10.1016/j.neurol.2023.08.005.
• Donato, Cristina, Daniella Balduino Victorino, Carolina Cabezas, Andrea Aguirre, Joana Lourenço, Marie-Claude Potier, Javier Zorrilla de San Martin, et Alberto Bacci. « Pharmacological Signature and Target Specificity of Inhibitory Circuits Formed by Martinotti Cells in the Mouse Barrel Cortex ». The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 43, n^o 1 (4 janvier 2023): 14‑27. https://doi.org/10.1523/JNEUROSCI.1661-21.2022.
• Dubreil, Laurence, Noreddine Damane, Romain Fleurisson, Marine Charrier, Julien Pichon, Isabelle Leroux, Cindy Schleder, et al. « Specific and Label-Free Endogenous Signature of Dystrophic Muscle by Synchrotron Deep Ultraviolet Radiation ». Scientific Reports 13, n^o 1 (4 juillet 2023): 10808. https://doi.org/10.1038/s41598-023-37762-1.
• Düchs, Matthias, Dragica Blazevic, Philipp Rechtsteiner, Cynthia Kenny, Thorsten Lamla, Sarah Low, Jimmy Savistchenko, et al. « AAV-Mediated Expression of a New Conformational Anti-Aggregated α-Synuclein Antibody Prolongs Survival in a Genetic Model of α-Synucleinopathies ». NPJ Parkinson’s Disease 9, n^o 1 (15 juin 2023): 91. https://doi.org/10.1038/s41531-023-00542-9.
• Ducongé, Frédéric. « Improvement of Aptamers by High-Throughput Sequencing of Doped-SELEX ». Methods in Molecular Biology (Clifton, N.J.) 2570 (2023): 85‑102. https://doi.org/10.1007/978-1-0716-2695-5_7.
• Duwat, Charlotte, Pauline Léal, Audrey Vautheny, Gwennaëlle Aurégan, Charlène Joséphine, Marie-Claude Gaillard, Anne-Sophie Hérard, et al. « Development of an AAV-Based Model of Tauopathy Targeting Retinal Ganglion Cells and the Mouse Visual Pathway to Study the Role of Microglia in Tau Pathology ». Neurobiology of Disease 181 (1 juin 2023): 106116. https://doi.org/10.1016/j.nbd.2023.106116.
• Elena-Real, Carlos A., Annika Urbanek, Xamuel L. Lund, Anna Morató, Amin Sagar, Aurélie Fournet, Alejandro Estaña, et al. « Multi-Site-Specific Isotopic Labeling Accelerates High-Resolution Structural Investigations of Pathogenic Huntingtin Exon-1 ». Structure (London, England: 1993) 31, n^o 6 (1 juin 2023): 644-650.e5. https://doi.org/10.1016/j.str.2023.04.003.
• Epelbaum, Stéphane, et Federica Cacciamani. « Clinical Assessment of Brain Disorders ». In Machine Learning for Brain Disorders, édité par Olivier Colliot. New York, NY: Humana, 2023. http://www.ncbi.nlm.nih.gov/books/NBK597487/.
• Fang, Li, Alex Mas Monteys, Alexandra Dürr, Megan Keiser, Congsheng Cheng, Akhil Harapanahalli, Pedro Gonzalez-Alegre, Beverly L. Davidson, et Kai Wang. « Haplotyping SNPs for Allele-Specific Gene Editing of the Expanded Huntingtin Allele Using Long-Read Sequencing ». HGG Advances 4, n^o 1 (12 janvier 2023): 100146. https://doi.org/10.1016/j.xhgg.2022.100146.
• Faouzi, Johann, Olivier Colliot, et Jean-Christophe Corvol. « Machine Learning for Parkinson’s Disease and Related Disorders ». In Machine Learning for Brain Disorders, édité par Olivier Colliot. New York, NY: Humana, 2023. http://www.ncbi.nlm.nih.gov/books/NBK597492/.
• Fayard, Audrey, Alexis Fenyi, Sonia Lavisse, Sandra Dovero, Luc Bousset, Tracy Bellande, Sophie Lecourtois, et al. « Functional and Neuropathological Changes Induced by Injection of Distinct Alpha-Synuclein Strains: A Pilot Study in Non-Human Primates ». Neurobiology of Disease 180 (mai 2023): 106086. https://doi.org/10.1016/j.nbd.2023.106086.
• Fevga, Christina, Christelle Tesson, Ana Carreras Mascaro, Thomas Courtin, Riaan van Coller, Salma Sakka, Federico Ferraro, et al. « PTPA Variants and Impaired PP2A Activity in Early-Onset Parkinsonism with Intellectual Disability ». Brain: A Journal of Neurology 146, n^o 4 (19 avril 2023): 1496‑1510. https://doi.org/10.1093/brain/awac326.
• Frisoni, Giovanni B., Daniele Altomare, Federica Ribaldi, Nicolas Villain, Carol Brayne, Naaheed Mukadam, Marc Abramowicz, et al. « Dementia Prevention in Memory Clinics: Recommendations from the European Task Force for Brain Health Services ». The Lancet Regional Health. Europe 26 (mars 2023): 100576. https://doi.org/10.1016/j.lanepe.2022.100576.
• Fürtjes, Anna E., James H. Cole, Baptiste Couvy-Duchesne, et Stuart J. Ritchie. « A Quantified Comparison of Cortical Atlases on the Basis of Trait Morphometricity ». Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 158 (janvier 2023): 110‑26. https://doi.org/10.1016/j.cortex.2022.11.001.
• Garin, Clément M., et Marc Dhenain. « Mean Amplitude of Low Frequency Fluctuations Measured by fMRI at 11.7 T in the Aging Brain of Mouse Lemur Primate ». Scientific Reports 13, n^o 1 (17 mai 2023): 7970. https://doi.org/10.1038/s41598-023-33482-8.
• Gavoille, Antoine, Fabien Rollot, Romain Casey, Marc Debouverie, Emmanuelle Le Page, Jonathan Ciron, Jerome De Seze, et al. « Investigating the Long-Term Effect of Pregnancy on the Course of Multiple Sclerosis Using Causal Inference ». Neurology 100, n^o 12 (21 mars 2023): e1296‑1308. https://doi.org/10.1212/WNL.0000000000206774.
• Genovese, Guglielmo, Belén Diaz-Fernandez, François-Xavier Lejeune, Itamar Ronen, Małgorzata Marjańska, Lydia Yahia-Cherif, Stéphane Lehéricy, Francesca Branzoli, et Charlotte Rosso. « Longitudinal Monitoring of Microstructural Alterations in Cerebral Ischemia with in Vivo Diffusion-Weighted MR Spectroscopy ». Radiology 306, n^o 3 (mars 2023): e220430. https://doi.org/10.1148/radiol.220430.
• Géraudie, Amandine, Maximilien Riche, Thaïs Lestra, Alexandre Trotier, Léo Dupuis, Bertrand Mathon, Alexandre Carpentier, et Benoît Delatour. « Effects of Low-Intensity Pulsed Ultrasound-Induced Blood-Brain Barrier Opening in P301S Mice Modeling Alzheimer’s Disease Tauopathies ». International Journal of Molecular Sciences 24, n^o 15 (3 août 2023): 12411. https://doi.org/10.3390/ijms241512411.
• Gharbi-Meliani, Amin, François Husson, Henri Vandendriessche, Eleonore Bayen, Kristine Yaffe, Anne-Catherine Bachoud-Lévi, et Laurent Cleret de Langavant. « Identification of High Likelihood of Dementia in Population-Based Surveys Using Unsupervised Clustering: A Longitudinal Analysis ». Alzheimer’s Research & Therapy 15, n^o 1 (29 novembre 2023): 209. https://doi.org/10.1186/s13195-023-01357-9.
• Grandjean, Joanes, Gabriel Desrosiers-Gregoire, Cynthia Anckaerts, Diego Angeles-Valdez, Fadi Ayad, David A. Barrière, Ines Blockx, et al. « A Consensus Protocol for Functional Connectivity Analysis in the Rat Brain ». Nature Neuroscience 26, n^o 4 (avril 2023): 673‑81. https://doi.org/10.1038/s41593-023-01286-8.
• Grasset, Leslie, Vincent Planche, Vincent Bouteloup, Chabha Azouani, Bruno Dubois, Frédéric Blanc, Claire Paquet, et al. « Physical Activity, Biomarkers of Brain Pathologies and Dementia Risk: Results from the Memento Clinical Cohort ». Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 19, n^o 12 (décembre 2023): 5700‑5718. https://doi.org/10.1002/alz.13360.
• Gribaudo, Simona, Luc Bousset, Josquin Courte, Ronald Melki, Jean-Michel Peyrin, et Anselme L. Perrier. « Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions ». Methods in Molecular Biology (Clifton, N.J.) 2551 (2023): 357‑78. https://doi.org/10.1007/978-1-0716-2597-2_24.
• Guillaume-Jugnot, P., N. Shor, F. Bielle, C. Zavanone, S. Barete, et E. Maillart. « Atypical Multiple Sclerosis Associated with Indolent Systemic Mastocytosis Treated by Cladribine ». Revue Neurologique 179, n^o 8 (octobre 2023): 925‑27. https://doi.org/10.1016/j.neurol.2023.03.020.
• Hardy, Eléonore, Julien Moulard, Augustin Walter, Pascal Ezan, Alexis-Pierre Bemelmans, Franck Mouthon, Mathieu Charvériat, Nathalie Rouach, et Armelle Rancillac. « Upregulation of Astroglial Connexin 30 Impairs Hippocampal Synaptic Activity and Recognition Memory ». PLoS Biology 21, n^o 4 (avril 2023): e3002075. https://doi.org/10.1371/journal.pbio.3002075.
• Heinzmann, Anna, Sabrina Sayah, François-Xavier Lejeune, Valérie Hahn, Marc Teichmann, Marie-Lorraine Monin, Enrica Marchionni, et al. « Huntington’s Disease with Small CAG Repeat Expansions ». Movement Disorders: Official Journal of the Movement Disorder Society 38, n^o 7 (juillet 2023): 1294‑1306. https://doi.org/10.1002/mds.29427.
• Henriet, Esther, Elodie M. Martin, Pauline Jubin, Dominique Langui, Abdelkrim Mannioui, Bruno Stankoff, Catherine Lubetzki, Arseny Khakhalin, et Bernard Zalc. « Monitoring Recovery after CNS Demyelination, a Novel Tool to de-Risk pro-Remyelinating Strategies ». Brain: A Journal of Neurology 146, n^o 6 (1 juin 2023): 2453‑63. https://doi.org/10.1093/brain/awad051.
• Hours, Camille M., Sophie Gil, et Pierre Gressens. « Molecular and Cellular Insights: A Focus on Glycans and the HNK1 Epitope in Autism Spectrum Disorder ». International Journal of Molecular Sciences 24, n^o 20 (13 octobre 2023): 15139. https://doi.org/10.3390/ijms242015139.
• Janssen, Olin, Willemijn J. Jansen, Stephanie J. B. Vos, Merce Boada, Lucilla Parnetti, Tomasz Gabryelewicz, Tormod Fladby, et al. « Characteristics of Subjective Cognitive Decline Associated with Amyloid Positivity ». Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 18, n^o 10 (octobre 2022): 1832‑45. https://doi.org/10.1002/alz.12512.
• Lanore, Aymeric, Fanny Casse, Christelle Tesson, Thomas Courtin, Poornima Jayadev Menon, Sara Sambin, Graziella Mangone, et al. « Differences in Survival across Monogenic Forms of Parkinson’s Disease ». Annals of Neurology 94, n^o 1 (juillet 2023): 123‑32. https://doi.org/10.1002/ana.26636.
• Le Stanc, Lorna, Katia Youssov, Maria Giavazzi, Agnès Sliwinski, Anne-Catherine Bachoud-Lévi, et Charlotte Jacquemot. « Language Disorders in Patients with Striatal Lesions: Deciphering the Role of the Striatum in Language Performance ». Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 166 (septembre 2023): 91‑106. https://doi.org/10.1016/j.cortex.2023.04.016.
• Lemoine, Laurie, Marine Lunven, Nicolas Fraisse, Katia Youssov, Blanche Bapst, Graça Morgado, Ralf Reilmann, et al. « The Striatum in Time Production: The Model of Huntington’s Disease in Longitudinal Study ». Neuropsychologia 179 (28 janvier 2023): 108459. https://doi.org/10.1016/j.neuropsychologia.2022.108459.
• Levraut, Michael, Sabine Laurent-Chabalier, Xavier Ayrignac, Kévin Bigaut, Manon Rival, Sanae Squalli, Hélène Zéphir, et al. « Kappa Free Light Chain Biomarkers Are Efficient for the Diagnosis of Multiple Sclerosis: A Large Multicenter Cohort Study ». Neurology(R) Neuroimmunology & Neuroinflammation 10, n^o 1 (janvier 2023): e200049. https://doi.org/10.1212/NXI.0000000000200049.
• Liu, Ganqiang, Chunming Ni, Jiamin Zhan, Weimin Li, Junfeng Luo, Zhixiang Liao, Joseph J. Locascio, et al. « Mitochondrial Haplogroups and Cognitive Progression in Parkinson’s Disease ». Brain: A Journal of Neurology 146, n^o 1 (5 janvier 2023): 42‑49. https://doi.org/10.1093/brain/awac327.
• Liu, Kathy Y., Nicolas Villain, Scott Ayton, Sarah F. Ackley, Vincent Planche, Robert Howard, et Madhav Thambisetty. « Key Questions for the Evaluation of Anti-Amyloid Immunotherapies for Alzheimer’s Disease ». Brain Communications 5, n^o 3 (2023): fcad175. https://doi.org/10.1093/braincomms/fcad175.
• Louapre, C., M. Rosenzwajg, M. Golse, A. Roux, F. Pitoiset, L. Adda, N. Tchitchek, et al. « A Randomized Double-Blind Placebo-Controlled Trial of Low-Dose Interleukin-2 in Relapsing-Remitting Multiple Sclerosis ». Journal of Neurology 270, n^o 9 (septembre 2023): 4403‑14. https://doi.org/10.1007/s00415-023-11690-6.
• Lunven, Marine, Karen Hernandez Dominguez, Katia Youssov, Jennifer Hamet Bagnou, Rafika Fliss, Henri Vandendriessche, Blanche Bapst, et al. « A New Approach to Digitized Cognitive Monitoring: Validity of the SelfCog in Huntington’s Disease ». Brain Communications 5, n^o 2 (2023): fcad043. https://doi.org/10.1093/braincomms/fcad043.
• Lunven, Marine, Monica N. Toba, et Paolo Bartolomeo. « Prism Adaptation Therapy in Spatial Neglect: The Importance of Connectional Anatomy ». Neuropsychologia 188 (9 septembre 2023): 108640. https://doi.org/10.1016/j.neuropsychologia.2023.108640.
• Maalouf, Elise, Souheil Hallit, Pascale Salameh, et Hassan Hosseini. « Depression, Anxiety, Insomnia, Stress, and the Way of Coping Emotions as Risk Factors for Ischemic Stroke and Their Influence on Stroke Severity: A Case-Control Study in Lebanon ». Frontiers in Psychiatry 14 (2023): 1097873. https://doi.org/10.3389/fpsyt.2023.1097873.
• Maalouf E, Hallit S, Salameh P, Hosseini H. « Eating Behaviors, Lifestyle, and Ischemic Stroke: A Lebanese Case-Control Study ». International Journal of Environmental Research and Public Health 20, n^o 2 (13 janvier 2023): 1487. https://doi.org/10.3390/ijerph20021487.
• Maalouf E, Hallit S, Salameh P, Hosseini H.  « Impact of Preexisting Alcohol Use Disorder, Bipolar Disorder, and Schizophrenia on Ischemic Stroke Risk and Severity: A Lebanese Case-Control Study ». Healthcare (Basel, Switzerland) 11, n^o 4 (11 février 2023): 538. https://doi.org/10.3390/healthcare11040538.
• Maheux, Etienne, Igor Koval, Juliette Ortholand, Colin Birkenbihl, Damiano Archetti, Vincent Bouteloup, Stéphane Epelbaum, Carole Dufouil, Martin Hofmann-Apitius, et Stanley Durrleman. « Forecasting Individual Progression Trajectories in Alzheimer’s Disease ». Nature Communications 14, n^o 1 (10 février 2023): 761. https://doi.org/10.1038/s41467-022-35712-5.
• Malaeb, Diana, Sarah Cherri, Iqbal Fahs, Hala Sacre, Emane Abdallah, Pascale Salameh, et Hassan Hosseini. « Management of Acute Stroke Among Lebanese Patients: Assessing Adherence to International Guidelines ». Current Drug Safety, 18 novembre 2022. https://doi.org/10.2174/1574886318666221118151504.
• Malaeb, Diana, Hala Sacre, Sara Mansour, Chadia Haddad, Abir Sarray El Dine, Tamara Fleihan, Souheil Hallit, Pascale Salameh, et Hassan Hosseini. « Assessment of Medication Adherence among Lebanese Adult Patients with Non-Communicable Diseases during COVID-19 Lockdown: A Cross-Sectional Study ». Frontiers in Public Health 11 (2023): 1145016. https://doi.org/10.3389/fpubh.2023.1145016.
• Marques, Ana, Elise Macias, Bruno Pereira, Elodie Durand, Carine Chassain, Tiphaine Vidal, Luc Defebvre, et al. « Volumetric Changes and Clinical Trajectories in Parkinson’s Disease: A Prospective Multicentric Study ». Journal of Neurology 270, n^o 12 (décembre 2023): 6033‑43. https://doi.org/10.1007/s00415-023-11947-0.
• Martínez Carrasco, Alejandro, Raquel Real, Michael Lawton, Regina Hertfelder Reynolds, Manuela Tan, Lesley Wu, Nigel Williams, et al. « Genome-Wide Analysis of Motor Progression in Parkinson Disease ». Neurology. Genetics 9, n^o 5 (octobre 2023): e200092. https://doi.org/10.1212/NXG.0000000000200092.
• Martín-Gómez, Carmen, Juan Dario Ortigoza-Escobar, Laia Nou-Fontanet, Juan M. Molina-Linde, Anne-Catherine Bachoud-Lévi, Juliane Léger, Juan Antonio Blasco-Amaro, et NKX2-1-Related Disorders Guideline Working Group. « Exploring the Values, Preferences, and Information Needs of Patients with NKX2-1-Related Disorders: A Qualitative Study Protocol ». PloS One 18, n^o 2 (2023): e0281573. https://doi.org/10.1371/journal.pone.0281573.
• Masingue, M., G. Fernández-Eulate, R. Debs, C. Tard, C. Labeyrie, S. Leonard-Louis, C.-M. Dhaenens, M. A. Masson, P. Latour, et T. Stojkovic. « Strategy for Genetic Analysis in Hereditary Neuropathy ». Revue Neurologique 179, n^o 1‑2 (2023): 10‑29. https://doi.org/10.1016/j.neurol.2022.11.007.
• Masson, Mary-Amélie, et Brahim Nait-Oumesmar. « Emerging Concepts in Oligodendrocyte and Myelin Formation, Inputs from the Zebrafish Model ». Glia 71, n^o 5 (mai 2023): 1147‑63. https://doi.org/10.1002/glia.24336.
• McColgan, Peter, Alpa Thobhani, Lauren Boak, Scott A. Schobel, Alessia Nicotra, Giuseppe Palermo, Dylan Trundell, et al. « Tominersen in Adults with Manifest Huntington’s Disease ». The New England Journal of Medicine 389, n^o 23 (7 décembre 2023): 2203‑5. https://doi.org/10.1056/NEJMc2300400.
• Megat, Salim, Natalia Mora, Jason Sanogo, Olga Roman, Alberto Catanese, Najwa Ouali Alami, Axel Freischmidt, et al. « Integrative Genetic Analysis Illuminates ALS Heritability and Identifies Risk Genes ». Nature Communications 14, n^o 1 (20 janvier 2023): 342. https://doi.org/10.1038/s41467-022-35724-1.
• Millet, Bruno, Stéphane Mouchabac, Gabriel Robert, Redwan Maatoug, Thibaut Dondaine, Florian Ferreri, et Alexis Bourla. « Transcranial Magnetic Stimulation (rTMS) on the Precuneus in Alzheimer’s Disease: A Literature Review ». Brain Sciences 13, n^o 9 (15 septembre 2023): 1332. https://doi.org/10.3390/brainsci13091332.
• Molloy, Eleanor J., Aoife Branagan, Tim Hurley, Fiona Quirke, Declan Devane, Petek E. Taneri, Mohamed El-Dib, et al. « Neonatal Encephalopathy and Hypoxic-Ischemic Encephalopathy: Moving from Controversy to Consensus Definitions and Subclassification ». Pediatric Research 94, n^o 6 (décembre 2023): 1860‑63. https://doi.org/10.1038/s41390-023-02775-z.
• Moreau, Caroline, Tiphaine Rouaud, David Grabli, Isabelle Benatru, Philippe Remy, Ana-Raquel Marques, Sophie Drapier, et al. « Overview on Wearable Sensors for the Management of Parkinson’s Disease ». NPJ Parkinson’s Disease 9, n^o 1 (2 novembre 2023): 153. https://doi.org/10.1038/s41531-023-00585-y.
• Morin, Cécile, Cindy Bokobza, Bobbi Fleiss, Elisa L. Hill-Yardin, Juliette Van Steenwinckel, et Pierre Gressens. « Preterm Birth by Cesarean Section: The Gut-Brain Axis, a Key Regulator of Brain Development ». Developmental Neuroscience, 15 septembre 2023. https://doi.org/10.1159/000534124.
• Nascimento, G. C., M. Bortolanza, A. Bribian, G. C. Leal-Luiz, R. Raisman-Vozari, L. López-Mascaraque, et E. Del-Bel. « Dynamic Involvement of Striatal NG2-Glia in L-DOPA Induced Dyskinesia in Parkinsonian Rats: Effects of Doxycycline ». ASN Neuro 15 (2023): 17590914231155976. https://doi.org/10.1177/17590914231155976.
• Nguyen, Linda T., Andrea Aprico, Eze Nwoke, Alexander D. Walsh, Farrah Blades, Raphael Avneri, Elodie Martin, Bernard Zalc, Trevor J. Kilpatrick, et Michele D. Binder. « Mertk-Expressing Microglia Influence Oligodendrogenesis and Myelin Modelling in the CNS ». Journal of Neuroinflammation 20, n^o 1 (6 novembre 2023): 253. https://doi.org/10.1186/s12974-023-02921-8.
• Nobileau, Alexis, Rahul Gaurav, Lydia Chougar, Alice Faucher, Romain Valabrègue, Graziella Mangone, Smaranda Leu-Semenescu, et al. « Neuromelanin-Sensitive Magnetic Resonance Imaging Changes in the Locus Coeruleus/Subcoeruleus Complex in Patients with Typical and Atypical Parkinsonism ». Movement Disorders: Official Journal of the Movement Disorder Society, 2 janvier 2023. https://doi.org/10.1002/mds.29309.
• Olivier, Paul, Pierre Gressens, et Catherine Barthelemy. « Neurodevelopmental Disorders: Research and Interventions beyond Classifications ». Journal of Neural Transmission (Vienna, Austria: 1996) 130, n^o 3 (mars 2023): 181‑84. https://doi.org/10.1007/s00702-023-02596-8.
• Ortholand, Juliette, Pierre-François Pradat, Sophie Tezenas du Montcel, et Stanley Durrleman. « Interaction of Sex and Onset Site on the Disease Trajectory of Amyotrophic Lateral Sclerosis ». Journal of Neurology 270, n^o 12 (décembre 2023): 5903‑12. https://doi.org/10.1007/s00415-023-11932-7.
• Oudart, Marc, Katia Avila-Gutierrez, Clara Moch, Elena Dossi, Giampaolo Milior, Anne-Cécile Boulay, Mathis Gaudey, et al. « The Ribosome-Associated Protein RACK1 Represses Kir4.1 Translation in Astrocytes and Influences Neuronal Activity ». Cell Reports 42, n^o 5 (30 mai 2023): 112456. https://doi.org/10.1016/j.celrep.2023.112456.
• Pantazopoulou, Marina, Agaristi Lamprokostopoulou, Dimitra Sotiria Karampela, Anastasia Alexaki, Anastasios Delis, Audrey Coens, Martina Samiotaki, et al. « Differential Intracellular Trafficking of Extracellular Vesicles in Microglia and Astrocytes ». Cellular and Molecular Life Sciences: CMLS 80, n^o 7 (30 juin 2023): 193. https://doi.org/10.1007/s00018-023-04841-5.
• Parrales-Macias, Valeria, Patrick P. Michel, Aurore Tourville, Rita Raisman-Vozari, Stéphane Haïk, Stéphane Hunot, Nicolas Bizat, et Annie Lannuzel. « The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and C. Elegans Worms ». Cells 12, n^o 9 (7 mai 2023): 1336. https://doi.org/10.3390/cells12091336.
• Peyronneau, M. A., B. Kuhnast, D.-L. Nguyen, B. Jego, G. Sayet, F. Caillé, S. Lavisse, et al. « [18F]DPA-714: Effect of Co-Medications, Age, Sex, BMI and TSPO Polymorphism on the Human Plasma Input Function ». European Journal of Nuclear Medicine and Molecular Imaging, 9 juin 2023. https://doi.org/10.1007/s00259-023-06286-1.
• Pinto, Serge, Adelheid Nebel, Jörn Rau, Robert Espesser, Pauline Maillochon, Oliver Niebuhr, Paul Krack, et al. « Results of a Randomized Clinical Trial of Speech After Early Neurostimulation in Parkinson’s Disease ». Movement Disorders: Official Journal of the Movement Disorder Society 38, n^o 2 (février 2023): 212‑22. https://doi.org/10.1002/mds.29282.
• Piroska, Leonard, Alexis Fenyi, Scott Thomas, Marie-Aude Plamont, Virginie Redeker, Ronald Melki, et Zoher Gueroui. « α-Synuclein Liquid Condensates Fuel Fibrillar α-Synuclein Growth ». Science Advances 9, n^o 33 (18 août 2023): eadg5663. https://doi.org/10.1126/sciadv.adg5663.
• Planche, Vincent, Vincent Bouteloup, Isabelle Pellegrin, Jean-Francois Mangin, Bruno Dubois, Pierre-Jean Ousset, Florence Pasquier, et al. « Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort ». Neurology 100, n^o 5 (31 janvier 2023): e473‑84. https://doi.org/10.1212/WNL.0000000000201479.
• Planche, Vincent, et Nicolas Villain. « Advocating for Demonstration of Disease Modification-Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly? » JAMA Neurology 80, n^o 7 (1 juillet 2023): 659‑60. https://doi.org/10.1001/jamaneurol.2023.0815.
• Portugal, Berta, Fanny Artaud, Cloé Domenighetti, Emmanuel Roze, Isabelle Degaey, Marianne Canonico, et Alexis Elbaz. « Body Mass Index, Abdominal Adiposity, and Incidence of Parkinson Disease in French Women From the E3N Cohort Study ». Neurology 100, n^o 3 (17 janvier 2023): e324‑35. https://doi.org/10.1212/WNL.0000000000201468.
• Pourabdolhossein, Fereshteh, Samaneh Dehghan, Anne Baron-Van Evercooren, et Beatriz Garcia-Diaz. « Editorial: Activation and Stimulation of Endogenous Neural Stem/Progenitor Cells in Multiple Sclerosis and Other Neurodegenerative Diseases ». Frontiers in Cellular Neuroscience 17 (2023): 1305767. https://doi.org/10.3389/fncel.2023.1305767.
• Pravata, M.v., P. Gressens, et S. andCappello. « Clinical and Molecular Overview of Cortical Malformations ». In Neocortical Neurogenesis in Development and Evolution, 595‑624. John Wiley & Sons, Ltd, 2023. https://doi.org/10.1002/9781119860914.ch27.
• Ramirez, Denise M. O., Jennifer D. Whitesell, Nikhil Bhagwat, Talitha L. Thomas, Apoorva D. Ajay, Ariana Nawaby, Benoît Delatour, et al. « Endogenous Pathology in Tauopathy Mice Progresses via Brain Networks ». bioRxiv: The Preprint Server for Biology, 24 mai 2023, 2023.05.23.541792. https://doi.org/10.1101/2023.05.23.541792.
• Razafimahatratra, Solofo, Thomas Guieysse, François-Xavier Lejeune, Marion Houot, Takfarinas Medani, Gérard Dreyfus, André Klarsfeld, et al. « Can a Failure in the Error-Monitoring System Explain Unawareness of Memory Deficits in Alzheimer’s Disease? » Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 166 (septembre 2023): 428‑40. https://doi.org/10.1016/j.cortex.2023.05.014.
• Real, Raquel, Alejandro Martinez-Carrasco, Regina H. Reynolds, Michael A. Lawton, Manuela M. X. Tan, Maryam Shoai, Jean-Christophe Corvol, et al. « Association between the LRP1B and APOE Loci and the Development of Parkinson’s Disease Dementia ». Brain: A Journal of Neurology 146, n^o 5 (2 mai 2023): 1873‑87. https://doi.org/10.1093/brain/awac414.
• Riquelme-Perez, Miriam, Fernando Perez-Sanz, Jean-François Deleuze, Carole Escartin, Eric Bonnet, et Solène Brohard. « DEVEA: An Interactive Shiny Application for Differential Expression Analysis, Data Visualization and Enrichment Analysis of Transcriptomics Data ». F1000Research 11 (2022): 711. https://doi.org/10.12688/f1000research.122949.2.
• Rouault, Marion, Inês Pereira, Herman Galioulline, Stephen M. Fleming, Klaas Enno Stephan, et Zina-Mary Manjaly. « Interoceptive and Metacognitive Facets of Fatigue in Multiple Sclerosis ». The European Journal of Neuroscience 58, n^o 2 (juillet 2023): 2603‑22. https://doi.org/10.1111/ejn.16048.
• Sabathé, Camille, Romain Casey, Sandra Vukusic, Emmanuelle Leray, Guillaume Mathey, Jérôme De Sèze, Jonathan Ciron, et al. « Improving the Decision to Switch from First- to Second-Line Therapy in Multiple Sclerosis: A Dynamic Scoring System ». Multiple Sclerosis (Houndmills, Basingstoke, England) 29, n^o 2 (février 2023): 236‑47. https://doi.org/10.1177/13524585221139156.
• Salaün, Jean-Philippe, Audrey Chagnot, Arnaud Cachia, Nicolas Poirel, Valérie Datin-Dorrière, Cléo Dujarrier, Eloïse Lemarchand, et al. « Consequences of General Anesthesia in Infancy on Behavior and Brain Structure ». Anesthesia and Analgesia 136, n^o 2 (1 février 2023): 240‑50. https://doi.org/10.1213/ANE.0000000000006233.
• Sauty, Benoît, et Stanley Durrleman. « Impact of Sex and APOE-Ε4 Genotype on Patterns of Regional Brain Atrophy in Alzheimer’s Disease and Healthy Aging ». Frontiers in Neurology 14 (2023): 1161527. https://doi.org/10.3389/fneur.2023.1161527.
• Shabani, Khadijeh, et Bassem A. Hassan. « The Brain on Time: Links between Development and Neurodegeneration ». Development (Cambridge, England) 150, n^o 10 (15 mai 2023): dev200397. https://doi.org/10.1242/dev.200397.
• Shabani, Khadijeh, Julien Pigeon, Marwan Benaissa Touil Zariouh, Tengyuan Liu, Azadeh Saffarian, Jun Komatsu, Elise Liu, et al. « The Temporal Balance between Self-Renewal and Differentiation of Human Neural Stem Cells Requires the Amyloid Precursor Protein ». Science Advances 9, n^o 24 (16 juin 2023): eadd5002. https://doi.org/10.1126/sciadv.add5002.
• Tonietto, Matteo, Emilie Poirion, Andrea Lazzarotto, Vito Ricigliano, Caroline Papeix, Michel Bottlaender, Benedetta Bodini, et Bruno Stankoff. « Periventricular Remyelination Failure in Multiple Sclerosis: A Substrate for Neurodegeneration ». Brain: A Journal of Neurology 146, n^o 1 (5 janvier 2023): 182‑94. https://doi.org/10.1093/brain/awac334.
• Torre-Muruzabal, Teresa, Anke Van der Perren, Audrey Coens, Géraldine Gelders, Anna Barber Janer, Sara Camacho-Garcia, Therése Klingstedt, et al. « Host Oligodendrogliopathy and α-Synuclein Strains Dictate Disease Severity in Multiple System Atrophy ». Brain: A Journal of Neurology 146, n^o 1 (5 janvier 2023): 237‑51. https://doi.org/10.1093/brain/awac061.
• Tortuyaux, Romain, Katia Avila-Gutierrez, Marc Oudart, Noémie Mazaré, Philippe Mailly, Jean-Christophe Deschemin, Sophie Vaulont, Carole Escartin, et Martine Cohen-Salmon. « Physiopathological Changes of Ferritin mRNA Density and Distribution in Hippocampal Astrocytes in the Mouse Brain ». Journal of Neurochemistry, 23 décembre 2022. https://doi.org/10.1111/jnc.15747.
• Tourville, Aurore, Sarah Viguier, Florencia González-Lizárraga, Rodrigo Hernán Tomas-Grau, Paola Ramirez, Jean-Michel Brunel, Mauricio Dos Santos Pereira, et al. « Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives ». Antioxidants (Basel, Switzerland) 12, n^o 3 (24 février 2023): 575. https://doi.org/10.3390/antiox12030575.
• Trenado, Carlos, Matthias Boschheidgen, Karim N’Diaye, Alfons Schnitzler, Luc Mallet, et Lars Wojtecki. « No Effect of Subthalamic Deep Brain Stimulation on Metacognition in Parkinson’s Disease ». Scientific Reports 13, n^o 1 (2 janvier 2023): 10. https://doi.org/10.1038/s41598-022-26980-8.
• Villain, N., V. Planche, et R. Levy. « High-Clearance Anti-Amyloid Immunotherapies in Alzheimer’s Disease. Part 2: Putative Scenarios and Timeline in Case of Approval, Recommendations for Use, Implementation, and Ethical Considerations in France ». Revue Neurologique 178, n^o 10 (décembre 2022): 999‑1010. https://doi.org/10.1016/j.neurol.2022.08.002.
• Villoria-González, Andrea, Bettina Zierfuss, Patricia Parzer, Elisabeth Heuböck, Violetta Zujovic, Petra Waidhofer-Söllner, Markus Ponleitner, et al. « Efficacy of HDAC Inhibitors in Driving Peroxisomal β-Oxidation and Immune Responses in Human Macrophages: Implications for Neuroinflammatory Disorders ». Biomolecules 13, n^o 12 (23 novembre 2023): 1696. https://doi.org/10.3390/biom13121696.
• Walton, Sara, Alexis Fenyi, Tyler Tittle, Ellen Sidransky, Gian Pal, Solji Choi, Ronald Melki, Bryan A. Killinger, et Jeffrey H. Kordower. « Neither Alpha-Synuclein-Preformed Fibrils Derived from Patients with GBA1 Mutations nor the Host Murine Genotype Significantly Influence Seeding Efficacy in the Mouse Olfactory Bulb ». bioRxiv: The Preprint Server for Biology, 25 août 2023, 2023.08.24.554646. https://doi.org/10.1101/2023.08.24.554646.
• Xicota, Laura, Julien Lagarde, Fanny Eysert, Benjamin Grenier-Boley, Isabelle Rivals, Alexandra Botté, Sylvie Forlani, et al. « Modifications of the Endosomal Compartment in Fibroblasts from Sporadic Alzheimer’s Disease Patients Are Associated with Cognitive Impairment ». Translational Psychiatry 13, n^o 1 (14 février 2023): 54. https://doi.org/10.1038/s41398-023-02355-z.
• Yazdan-Panah, Arya, Marius Schmidt-Mengin, Vito A. G. Ricigliano, Théodore Soulier, Bruno Stankoff, et Olivier Colliot. « Automatic Segmentation of the Choroid Plexuses: Method and Validation in Controls and Patients with Multiple Sclerosis ». NeuroImage. Clinical 38 (2023): 103368. https://doi.org/10.1016/j.nicl.2023.103368.
• Zack, Stephanie R., Roman Nikolaienko, Ben Cook, Ronald Melki, Aleksey V. Zima, et Edward M. Campbell. « Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy ». Research Square, 27 janvier 2023, rs.3.rs-2508369. https://doi.org/10.21203/rs.3.rs-2508369/v1.
• Zutterling, Caroline, Anne-Laure Todeschini, Deborah Fourmy, Didier Busso, Xavier Veaute, Frédéric Ducongé, et Reiner A. Veitia. « The Forkhead DNA-Binding Domain Binds Specific G2-Rich RNA Sequences ». Nucleic Acids Research 51, n^o 22 (11 décembre 2023): 12367‑80. https://doi.org/10.1093/nar/gkad994.

As part of NeurATRIS' support to students training, Anna Williams from the Institute for Regeneration and Repair at the University of Edinburgh will give a lecture on December 20, 2023 to the students of the Master 2 BIP. This lecture  will be followed by a discussion and lunch with students. All NeurATRIS members are welcome.

PASREL-Imagerie organizes the 2nd "Accelerating drug development using biomedical imaging" scientific day on February 9, 2024 at the Cité Internationale Universitaire in Paris.

Dedicated to all biomedical stakeholders, the event will highlight the translational role of MRI and Ultrasound in drug discovery.

The day will provide an opportunity to :

• Listen to innovative projects by industrial and academic partners
• Discover the latest advances with expert speakers on non-isotopic imaging to de-risk medical innovations
• Develop your network

  Online registration is free and compulsory before February 05, 2024 : https://accelerating-drug-development-2023.b2match.io/

Where?  Centre de congrès, Lyon

When? October 18 and 19, 2023

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Come and meet NeurATRIS on October 18 & 19, 2023, at the Rendez-Vous Carnot, the R&D meeting place for companies.

We'll be exhibiting in the research infrastructure village, stand U03.

Meet us to discuss your projects and find out more about NeurATRIS!

We look forward to hearing from you!
 

More info on the event.

The ICM's Histomics platform is organizing a workshop entirely dedicated to "Recent advances in spatial transcriptomics in the brain ". This event will take place at the ICM's Edmond and Lily Safra Auditorium, on November 03, 2023 from 9:00 am to 06:00 pm.

The objectives of this day are multiple: (i) to present spatial transcriptomics and review current knowledge and future challenges; (ii) to offer practical experience on how to analyze and interpret spatial transcriptomics data; (iii) to establish a network of experts and collaborators who can share their experience on spatial transcriptomics and its application in the brain (participants, speakers and industrial partners).

Registration is free but mandatory (limited number of places) before October 20, 2023, via this link or the QR code below.

The first "NeuroSpin Translational Meetings" will be held in Gif-sur-Yvette on 17 and 18 November 2023.

The aim of this conference is to bring together neuroimaging researchers and clinician scientists involved in clinical research, to discuss current issues relating to neurodevelopmental disorders.

Are you a clinician or a scientist? Are you involved in some way in clinical or basic neuroimaging research? Don't hesitate to register for these first NeuroSpin Translational Meetings!

More details and registration.

Join us on December 07, 2023 at the Centre International de Conférences Sorbonne Université in Paris for the NeurATRIS Annual General Meeting. 

This day will be an opportunity to take stock of the actions and results obtained to date, to exchange views on both the scientific activities of the NeurATRIS thematic work-packages and the collaborative projects carried out under the various calls for projects and to discuss the infrastructure's future.

More information on the programme and registration to follow here.

Mark your calendars!

In 2022, NeurATRIS celebrated 10 years of research into neurodegenerative and neurodevelopmental diseases.

The work carried out by our teams in the 4 main areas of neuroscience and neurology research - (1) Cell therapy, (2) Gene therapy, (3) Drug therapies and (4) In vivo evaluation and therapeutic efficacy - has resulted in the publication of more than 1,200 publications over the period 2012-2022, with a steadily increasing annual figure since 2018.

2022: NEURATRIS PUBLICATIONS 2022

2021: NEURATRIS PUBLICATIONS 2021

2020: NEURATRIS PUBLICATIONS 2020

2019: NEURATRIS PUBLICATIONS 2019

2018: NEURATRIS PUBLICATIONS 2018

2017: NEURATRIS PUBLICATIONS 2017

Don't miss the opportunity to learn more about NeurATRIS at the NECTAR 2023 conference in Naples, Italy. Our Partnership Manager will be present throughout the conference.

Conference registration. 

Congratulations to Tom Lakomy, PhD student at MIRCen (CEA), who has won the NeurATRIS prize for the best scientific image of 2022-2023. This prize is awarded as part of the MIRCenImage contest: "Ta science en image", organized by the MIRCen department at CEA Fontenay-aux-Roses.

"GFAP immunostaining of tanycytes near the third ventricule with co-staining of STAT3+ cells in a mouse brain"

NeurATRIS co-organizes with the Microglia and Neuroinflammation GDR, the "Microglia from genes to functions" workshop, which will take place from November 27 to December 01, 2023, at the Bordeaux School of Neuroscience.

The aim of this first edition is to provide a comprehensive 5-day training course on current topics in microglia research. The program covers three aspects: (1) understanding and analyzing omics data (2) characterizing microglial metabolism (3) analyzing microglia morphology and dynamics using ex vivo and in vivo 2-photon microscopy approaches.

More information.

NeurATRIS supports the Workshop on Diffusion MRI, which will take place from September 5 to 8, 2023, in Cardiff.

The aim is to introduce scientists and clinicians working in the field of medical imaging to diffusion-weighted magnetic resonance imaging and train them to undertake the first basic steps towards using this technique in clinical and preclinical settings.

As part of its support for the training of young researchers, NeurATRIS is offering 5 stipends.

Application deadline: October 31, 2023.

More details and registration.

Registration for the 5-day course on “Translational Medicine Explained (TMex) ” in November 2023 in Berlin is now open !

The TMex Winter School is targeted to PhD/MD students in the second half of their PhD, postdocs and other young scientists who are involved in biomedical research. 

The course covers a variety of activities, including a drug discovery game, elevator pitches, group work and lectures. Experts from academia and industry will be addressing essential elements of the translational pipeline such as target product profiles, research and development of biologics, clinical trials, regulatory support, science communication, patient-driven research and personalised medicine. Several innovation sessions will take place, covering novel drug delivery methods and academia-biotech-industry collaboration. 

Dates: 13- 17 November 2023, 9:00 - 18:00 CET

Location : Bayer Pharmaceuticals Headquarters, Berlin, Germany

More info and registration

We'll be exibiting at AFSSI Connexions in Montpellier on 4 and 5 July ! ☀️

Meet us on our stand in the heart of the exhibition area to discuss your projects?

We're proud to be taking part in this highlight of @AFSSI Life Sciences!

These two days will be devoted to exchanges between French #services and #innovation companies and key players in the ecosystem?

Register to meet our team: https://bit.ly/InscriptionAC23

The NECTAR 2023 conference will be held in Naples, Italy, from 23 to 25 October 2023.

The aim of the conference is to present (1) recent advances in modelling human brain disorders and understanding the molecular mechanisms underlying central nervous system disorders, (2) recent developments in cell and gene therapies for Parkinson's and Huntington's diseases, (3) advances in gene therapy and cell transplantation for conditions such as spinal cord injury, amyotrophic lateral sclerosis and vision loss.

Registration : May 31 to September 1, 2023. 

More details.

In 2022, NeurATRIS research generated 235 publications in peer-reviewed journals. Many thanks to all our teams and collaborators, who work every day to advance translational neuroscience research!

• Alcalá-Vida, Rafael, Caroline Lotz, Baptiste Brulé, Jonathan Seguin, Charles Decraene, Ali Awada, Aurélie Bombardier, et al. « Altered Activity-Regulated H3K9 Acetylation at TGF-Beta Signaling Genes during Egocentric Memory in Huntington’s Disease ». Progress in Neurobiology 219 (décembre 2022): 102363. https://doi.org/10.1016/j.pneurobio.2022.102363.
• Alonso-Alconada, Daniel, Pierre Gressens, Xavier Golay, et Nicola J. Robertson. « Neurogenesis Is Reduced at 48 h in the Subventricular Zone Independent of Cell Death in a Piglet Model of Perinatal Hypoxia-Ischemia ». Frontiers in Pediatrics 10 (2022): 793189. https://doi.org/10.3389/fped.2022.793189.
• Androuin, Alexandre, Manon Thierry, Susana Boluda, Brainbank NeuroCEB Neuropathology Network, Asha Baskaran, Dominique Langui, Charles Duyckaerts, et al. « Alterations of Neuronal Lysosomes in Alzheimer’s Disease and in APPxPS1-KI Mice ». Journal of Alzheimer’s Disease: JAD 87, n^o 1 (2022): 273‑84. https://doi.org/10.3233/JAD-215692.
• Audouard, Emilie, Fanny Michel, Vanessa Pierroz, Taeuk Kim, Lisa Rousselot, Béatrix Gillet-Legrand, Gaëlle Dufayet-Chauffaut, et al. « Bioelectronic Cell-Based Device Provides a Strategy for the Treatment of the Experimental Model of Multiple Sclerosis ». Journal of Controlled Release: Official Journal of the Controlled Release Society 352 (décembre 2022): 994‑1008. https://doi.org/10.1016/j.jconrel.2022.11.008.
• Bachoud-Lévi, A.-C. « What Did We Learn from Neural Grafts in Huntington Disease? » Revue Neurologique 178, n^o 5 (mai 2022): 441‑49. https://doi.org/10.1016/j.neurol.2022.03.004.
• Bachoud-Lévi, Anne-Catherine, Alice Dormeuil, et Charlotte Jacquemot. « Improving Efficacy of Aphasia Rehabilitation by Using Core Assessment of Language Processing ». Annals of Physical and Rehabilitation Medicine 65, n^o 6 (novembre 2022): 101630. https://doi.org/10.1016/j.rehab.2022.101630.
• Bacq, Alexandre, Delphine Roussel, Thomas Bonduelle, Sara Zagaglia, Marina Maletic, Théo Ribierre, Homa Adle-Biassette, et al. « Cardiac Investigations in Sudden Unexpected Death in DEPDC5-Related Epilepsy ». Annals of Neurology 91, n^o 1 (janvier 2022): 101‑16. https://doi.org/10.1002/ana.26256.
• Balsiger, Fabian, Benedikt Wagner, Johann M. E. Jende, Benjamin Marty, Martin Bendszus, Olivier Scheidegger, et Felix T. Kurz. « Methodologies and MR Parameters in Quantitative Magnetic Resonance Neurography: A Scoping Review Protocol ». Methods and Protocols 5, n^o 3 (6 mai 2022): 39. https://doi.org/10.3390/mps5030039.
• Barbier, Mathieu, Melanie Bahlo, Alessandra Pennisi, Maxime Jacoupy, Rick M. Tankard, Claire Ewenczyk, Kayli C. Davies, et al. « Heterozygous PNPT1 Variants Cause Spinocerebellar Ataxia Type 25 ». Annals of Neurology 92, n^o 1 (juillet 2022): 122‑37. https://doi.org/10.1002/ana.26366.
• Barros, L. F., I. Ruminot, T. Sotelo-Hitschfeld, R. Lerchundi, et I. Fernández-Moncada. « Metabolic Recruitment in Brain Tissue ». Annual Review of Physiology, 21 octobre 2022. https://doi.org/10.1146/annurev-physiol-021422-091035.
• Bassignana, Giulia, Giordano Lacidogna, Paolo Bartolomeo, Olivier Colliot, et Fabrizio De Vico Fallani. « The Impact of Aging on Human Brain Network Target Controllability ». Brain Structure & Function 227, n^o 9 (décembre 2022): 3001‑15. https://doi.org/10.1007/s00429-022-02584-w.
• Bayen, Eléonore, Laurent Cleret de Langavant, Katia Youssov, et Anne-Catherine Bachoud-Lévi. « Informal Care in Huntington’s Disease: Assessment of Objective-Subjective Burden and Its Associated Risk and Protective Factors ». Annals of Physical and Rehabilitation Medicine 66, n^o 4 (2 décembre 2022): 101703. https://doi.org/10.1016/j.rehab.2022.101703.
• Beaudin, Marie, François Salachas, Pierre-François Pradat, et Nicolas Dupré. « Environmental Risk Factors for Amyotrophic Lateral Sclerosis: A Case-Control Study in Canada and France ». Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 23, n^o 7‑8 (novembre 2022): 592‑600. https://doi.org/10.1080/21678421.2022.2028167.
• Bellenguez, Céline, Fahri Küçükali, Iris E. Jansen, Luca Kleineidam, Sonia Moreno-Grau, Najaf Amin, Adam C. Naj, et al. « New Insights into the Genetic Etiology of Alzheimer’s Disease and Related Dementias ». Nature Genetics 54, n^o 4 (avril 2022): 412‑36. https://doi.org/10.1038/s41588-022-01024-z.
• Ben Haim, Lucile, et Carole Escartin. « Astrocytes and Neuropsychiatric Symptoms in Neurodegenerative Diseases: Exploring the Missing Links ». Current Opinion in Neurobiology 72 (février 2022): 63‑71. https://doi.org/10.1016/j.conb.2021.09.002.
• Benardais, Karelle, Isis M. Ornelas, Melissa Fauveau, Tanya L. Brown, Lisbet T. Finseth, Radmila Panic, Cyrille Deboux, Wendy B. Macklin, Teresa L. Wood, et Brahim Nait-Oumesmar. « P70S6 Kinase Regulates Oligodendrocyte Differentiation and Is Active in Remyelinating Lesions ». Brain Communications 4, n^o 1 (2022): fcac025. https://doi.org/10.1093/braincomms/fcac025.
• Benatar, Michael, Joanne Wuu, Caroline McHutchison, Ronald B. Postuma, Bradley F. Boeve, Ronald Petersen, Christopher A. Ross, et al. « Preventing Amyotrophic Lateral Sclerosis: Insights from Pre-Symptomatic Neurodegenerative Diseases ». Brain: A Journal of Neurology 145, n^o 1 (29 mars 2022): 27‑44. https://doi.org/10.1093/brain/awab404.
• Betrouni, Nacim, Caroline Moreau, Anne-Sophie Rolland, Nicolas Carrière, Romain Viard, Renaud Lopes, Gregory Kuchcinski, et al. « Can Dopamine Responsiveness Be Predicted in Parkinson’s Disease Without an Acute Administration Test? » Journal of Parkinson’s Disease 12, n^o 7 (2022): 2179‑90. https://doi.org/10.3233/JPD-223334.
• Bigarreau, Julie, Nathalie Rouach, Anselme L. Perrier, Franck Mouthon, et Mathieu Charvériat. « Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models ». International Journal of Molecular Sciences 23, n^o 3 (31 janvier 2022): 1684. https://doi.org/10.3390/ijms23031684.
• Blanc, Frederic, Vincent Bouteloup, Claire Paquet, Marie Chupin, Florence Pasquier, Audrey Gabelle, Mathieu Ceccaldi, et al. « Prodromal Characteristics of Dementia with Lewy Bodies: Baseline Results of the MEMENTO Memory Clinics Nationwide Cohort ». Alzheimer’s Research & Therapy 14, n^o 1 (19 juillet 2022): 96. https://doi.org/10.1186/s13195-022-01037-0.
• Bloms-Funke, Petra, Michael Schumacher, Song Liu, Diya Su, Jing Li, Philippe Liere, Rainer Rupprecht, et al. « A Novel Dual Mode-of-Action Anti-Hyperalgesic Compound in Rats Which Is Neuroprotective and Promotes Neuroregeneration ». European Journal of Pharmacology 923 (15 mai 2022): 174935. https://doi.org/10.1016/j.ejphar.2022.174935.
• Bokobza, Cindy, Alice Jacquens, David Guenoun, Blandine Bianco, Anne Galland, Maxime Pispisa, Alexandra Cruz, et al. « Targeting the Brain 5-HT7 Receptor to Prevent Hypomyelination in a Rodent Model of Perinatal White Matter Injuries ». Journal of Neural Transmission (Vienna, Austria: 1996), 6 novembre 2022. https://doi.org/10.1007/s00702-022-02556-8.
• Bokobza, Cindy, Alice Jacquens, Manuela Zinni, Valérie Faivre, Jennifer Hua, David Guenoun, Caroline Userovici, et al. « Magnetic Isolation of Microglial Cells from Neonate Mouse for Primary Cell Cultures ». Journal of Visualized Experiments: JoVE, n^o 185 (25 juillet 2022). https://doi.org/10.3791/62964.
• Bokobza, Cindy, Pooja Joshi, Anne-Laure Schang, Zsolt Csaba, Valérie Faivre, Amélie Montané, Anne Galland, et al. « MiR-146b Protects the Perinatal Brain against Microglia-Induced Hypomyelination ». Annals of Neurology 91, n^o 1 (janvier 2022): 48‑65. https://doi.org/10.1002/ana.26263.
• Bonvento, Gilles, Stéphane H. R. Oliet, et Aude Panatier. « Glycolysis-Derived L-Serine Levels versus PHGDH Expression in Alzheimer’s Disease ». Cell Metabolism 34, n^o 5 (3 mai 2022): 654‑55. https://doi.org/10.1016/j.cmet.2022.04.002.
• Bossi, Simon, Dhanasak Dhanasobhon, Graham C. R. Ellis-Davies, Jimena Frontera, Marcel de Brito Van Velze, Joana Lourenço, Alvaro Murillo, et al. « GluN3A Excitatory Glycine Receptors Control Adult Cortical and Amygdalar Circuits ». Neuron 110, n^o 15 (3 août 2022): 2438-2454.e8. https://doi.org/10.1016/j.neuron.2022.05.016.
• Bourdon, Audrey, Virginie François, Liwen Zhang, Aude Lafoux, Bodvael Fraysse, Gilles Toumaniantz, Thibaut Larcher, et al. « Evaluation of the Dystrophin Carboxy-Terminal Domain for Micro-Dystrophin Gene Therapy in Cardiac and Skeletal Muscles in the DMDmdx Rat Model ». Gene Therapy 29, n^o 9 (septembre 2022): 520‑35. https://doi.org/10.1038/s41434-022-00317-6.
• Boussac, Mathilde, Christophe Arbus, Olivier Colin, Chloé Laurencin, Alexandre Eusebio, Elodie Hainque, Jean Christophe Corvol, et al. « Personality Assessment with Temperament and Character Inventory in Parkinson’s Disease ». Parkinsonism & Related Disorders 103 (octobre 2022): 34‑41. https://doi.org/10.1016/j.parkreldis.2022.08.004.
• Boutros, Celina F., Walaa Khazaal, Maram Taliani, Najwane Said Sadier, Pascale Salameh, et Hassan Hosseini. « One-Year Recurrence of Stroke and Death in Lebanese Survivors of First-Ever Stroke: Time-to-Event Analysis ». Frontiers in Neurology 13 (2022): 973200. https://doi.org/10.3389/fneur.2022.973200.
• Bouzigues, Arabella, Lucy L. Russell, Georgia Peakman, Martina Bocchetta, Caroline V. Greaves, Rhian S. Convery, Emily Todd, et al. « Anomia Is Present Pre-Symptomatically in Frontotemporal Dementia Due to MAPT Mutations ». Journal of Neurology 269, n^o 8 (août 2022): 4322‑32. https://doi.org/10.1007/s00415-022-11068-0.
• Boyer, Manon, Paul Baudin, Chloé Stengel, Antoni Valero-Cabré, Ann M. Lohof, Stéphane Charpier, Rachel M. Sherrard, et Séverine Mahon. « In Vivo Low-Intensity Magnetic Pulses Durably Alter Neocortical Neuron Excitability and Spontaneous Activity ». The Journal of Physiology 600, n^o 17 (septembre 2022): 4019‑37. https://doi.org/10.1113/JP283244.
• Brašić, James Robert, Jack Alexander Goodman, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Samuel D. Martin, et al. « Fragile X Mental Retardation Protein and Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome: A Pilot Study ». Brain Sciences 12, n^o 3 (26 février 2022): 314. https://doi.org/10.3390/brainsci12030314.
• Brouillet, Emmanuel. « Extreme Conservation of the Poly-Glutamine Tract in Huntingtin Is Related to Neurodevelopmental Functions: The “Better” May Become the “Enemy of the Good” in the Course of Evolution ». Cell Death and Differentiation 29, n^o 2 (février 2022): 266‑68. https://doi.org/10.1038/s41418-021-00927-4.
• Burbidge, Kevin, David J. Rademacher, Jessica Mattick, Stephanie Zack, Andrea Grillini, Luc Bousset, Ochan Kwon, et al. « LGALS3 (Galectin 3) Mediates an Unconventional Secretion of SNCA/α-Synuclein in Response to Lysosomal Membrane Damage by the Autophagic-Lysosomal Pathway in Human Midbrain Dopamine Neurons ». Autophagy 18, n^o 5 (mai 2022): 1020‑48. https://doi.org/10.1080/15548627.2021.1967615.
• Cacciamani, Federica, Valérie Godefroy, Simona M. Brambati, Raffaella Migliaccio, Stéphane Epelbaum, et Maxime Montembeault. « Differential Patterns of Domain-Specific Cognitive Complaints and Awareness Across the Alzheimer’s Disease Spectrum ». Frontiers in Aging Neuroscience 14 (2022): 811739. https://doi.org/10.3389/fnagi.2022.811739.
• Canonico, Marianne, Fanny Artaud, Isabelle Degaey, Frédéric Moisan, Rahime Kabore, Berta Portugal, Thi Thu Ha Nguyen, et al. « Incidence of Parkinson’s Disease in French Women from the E3N Cohort Study over 27 Years of Follow-Up ». European Journal of Epidemiology 37, n^o 5 (mai 2022): 513‑23. https://doi.org/10.1007/s10654-022-00851-y.
• Chandrasekaran, Jayashree, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Dinesh K. Deelchand, Michal Považan, et al. « Clinically Meaningful Magnetic Resonance Endpoints Sensitive to Preataxic Spinocerebellar Ataxia Types 1 and 3 ». Annals of Neurology, 13 décembre 2022. https://doi.org/10.1002/ana.26573.
• Charrier, Marine, Judith Lorant, Rafael Contreras-Lopez, Gautier Téjédor, Christophe Blanquart, Blandine Lieubeau, Cindy Schleder, et al. « Human MuStem Cells Repress T-Cell Proliferation and Cytotoxicity through Both Paracrine and Contact-Dependent Pathways ». Stem Cell Research & Therapy 13, n^o 1 (10 janvier 2022): 7. https://doi.org/10.1186/s13287-021-02681-3.
• Chou, Qiao-Ling, Ania Alik, François Marquier, Ronald Melki, François Treussart, et Michel Simonneau. « Impact of α-Synuclein Fibrillar Strains and β-Amyloid Assemblies on Mouse Cortical Neurons Endo-Lysosomal Logistics ». ENeuro 9, n^o 3 (2022): ENEURO.0227-21.2022. https://doi.org/10.1523/ENEURO.0227-21.2022.
• Chougar, Lydia, Emina Arsovic, Rahul Gaurav, Emma Biondetti, Alice Faucher, Romain Valabrègue, Nadya Pyatigorskaya, et al. « Regional Selectivity of Neuromelanin Changes in the Substantia Nigra in Atypical Parkinsonism ». Movement Disorders: Official Journal of the Movement Disorder Society 37, n^o 6 (juin 2022): 1245‑55. https://doi.org/10.1002/mds.28988.
• Cleret de Langavant, Laurent, Emmanuel Roze, Aimée Petit, Benoit Tressières, Amin Gharbi-Meliani, Hugo Chaumont, Patrick Pierre Michel, et al. « Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism ». Movement Disorders: Official Journal of the Movement Disorder Society 37, n^o 12 (décembre 2022): 2355‑66. https://doi.org/10.1002/mds.29222.
• Cortese, Rosa, Marco Battaglini, Ferran Prados, Alessia Bianchi, Lukas Haider, Anu Jacob, Jacqueline Palace, et al. « Clinical and MRI Measures to Identify Non-Acute MOG-Antibody Disease in Adults ». Brain: A Journal of Neurology, 14 décembre 2022, awac480. https://doi.org/10.1093/brain/awac480.
• Dadgar-Kiani, Ehsan, Gregor Bieri, Ronald Melki, Aaron D. Gitler, et Jin Hyung Lee. « Mesoscale Connections and Gene Expression Empower Whole-Brain Modeling of α-Synuclein Spread, Aggregation, and Decay Dynamics ». Cell Reports 41, n^o 6 (8 novembre 2022): 111631. https://doi.org/10.1016/j.celrep.2022.111631.
• Daly, Timothy, Ignacio Mastroleo, et Raffaella Migliaccio. « Avoiding Over-Reliance on Multi-Domain Interventions for Dementia Prevention ». Journal of Alzheimer’s Disease: JAD 90, n^o 3 (2022): 989‑92. https://doi.org/10.3233/JAD-215647.
• De Cock, Valérie Cochen, Pauline Dodet, Smaranda Leu-Semenescu, Cécile Aerts, Giovanni Castelnovo, Beatriz Abril, Sophie Drapier, et al. « Safety and Efficacy of Subcutaneous Night-Time Only Apomorphine Infusion to Treat Insomnia in Patients with Parkinson’s Disease (APOMORPHEE): A Multicentre, Randomised, Controlled, Double-Blind Crossover Study ». The Lancet. Neurology 21, n^o 5 (mai 2022): 428‑37. https://doi.org/10.1016/S1474-4422(22)00085-0.
• De Giorgi, Francesca, Muhammed Bilal Abdul-Shukkoor, Marianna Kashyrina, Leslie-Ann Largitte, Francesco De Nuccio, Brice Kauffmann, Alons Lends, et al. « Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions ». Biomolecules 12, n^o 3 (11 mars 2022): 436. https://doi.org/10.3390/biom12030436.
• De Nicola, Alejandro F., María Meyer, Laura Garay, Maria Sol Kruse, Michael Schumacher, Rachida Guennoun, et Maria Claudia Gonzalez Deniselle. « Progesterone and Allopregnanolone Neuroprotective Effects in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis ». Cellular and Molecular Neurobiology 42, n^o 1 (janvier 2022): 23‑40. https://doi.org/10.1007/s10571-021-01118-y.
• Degos, Bertrand, Pierre Pouget, et Marcus Missal. « From Anticipation to Impulsivity in Parkinson’s Disease ». NPJ Parkinson’s Disease 8, n^o 1 (3 octobre 2022): 125. https://doi.org/10.1038/s41531-022-00393-w.
• Deuschl, Günther, Angelo Antonini, Joao Costa, Katarzyna Śmiłowska, Daniela Berg, Jean-Christophe Corvol, Giovanni Fabbrini, et al. « European Academy of Neurology/Movement Disorder Society-European Section Guideline on the Treatment of Parkinson’s Disease: I. Invasive Therapies ». Movement Disorders: Official Journal of the Movement Disorder Society 37, n^o 7 (juillet 2022): 1360‑74. https://doi.org/10.1002/mds.29066.
• Devos, David, Julien Labreuche, Olivier Rascol, Jean-Christophe Corvol, Alain Duhamel, Pauline Guyon Delannoy, Werner Poewe, et al. « Trial of Deferiprone in Parkinson’s Disease ». The New England Journal of Medicine 387, n^o 22 (1 décembre 2022): 2045‑55. https://doi.org/10.1056/NEJMoa2209254.
• Diaz Heijtz, Rochellys, Pierre Gressens, et Jonathan R. Swann. « Targeting Microbial Metabolites to Treat Autism ». Nature Medicine 28, n^o 3 (mars 2022): 448‑50. https://doi.org/10.1038/s41591-022-01711-8.
• Dietrich, Michael, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, et al. « Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models ». Neurology(R) Neuroimmunology & Neuroinflammation 9, n^o 3 (mai 2022): e1161. https://doi.org/10.1212/NXI.0000000000001161.
• Doan Ngoc, Tra-My, Gaëlle Tilly, Richard Danger, Orianne Bonizec, Christophe Masset, Pierrick Guérif, Sarah Bruneau, et al. « Effector Memory-Expressing CD45RA (TEMRA) CD8+ T Cells from Kidney Transplant Recipients Exhibit Enhanced Purinergic P2X4 Receptor-Dependent Proinflammatory and Migratory Responses ». Journal of the American Society of Nephrology: JASN 33, n^o 12 (décembre 2022): 2211‑31. https://doi.org/10.1681/ASN.2022030286.
• Domenighetti, Cloé, Venceslas Douillard, Pierre-Emmanuel Sugier, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Sandeep Grover, Patrick May, et al. « The Interaction between HLA-DRB1 and Smoking in Parkinson’s Disease Revisited ». Movement Disorders: Official Journal of the Movement Disorder Society 37, n^o 9 (septembre 2022): 1929‑37. https://doi.org/10.1002/mds.29133.
• Domenighetti, Cloé, Pierre-Emmanuel Sugier, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Sandeep Grover, Océane Mohamed, Berta Portugal, et al. « Dairy Intake and Parkinson’s Disease: A Mendelian Randomization Study ». Movement Disorders: Official Journal of the Movement Disorder Society 37, n^o 4 (avril 2022): 857‑64. https://doi.org/10.1002/mds.28902.
• Dos Santos Pereira, Maurício, Glauce Crivelaro do Nascimento, Mariza Bortolanza, Patrick Pierre Michel, Rita Raisman-Vozari, et Elaine Del Bel. « Doxycycline Attenuates L-DOPA-Induced Dyskinesia through an Anti-Inflammatory Effect in a Hemiparkinsonian Mouse Model ». Frontiers in Pharmacology 13 (2022): 1045465. https://doi.org/10.3389/fphar.2022.1045465.
• Douceau, Sara, Eloïse Lemarchand, Yannick Hommet, Laurent Lebouvier, Charlène Joséphine, Alexis-Pierre Bemelmans, Eric Maubert, Véronique Agin, et Denis Vivien. « PKCδ-Positive GABAergic Neurons in the Central Amygdala Exhibit Tissue-Type Plasminogen Activator: Role in the Control of Anxiety ». Molecular Psychiatry 27, n^o 4 (avril 2022): 2197‑2205. https://doi.org/10.1038/s41380-022-01455-4.
• Dubreil, Laurence, Mireille Ledevin, Caroline Hervet, Déborah Menard, Claire Philippe, François J. Michel, Thibaut Larcher, François Meurens, et Nicolas Bertho. « The Internal Conduit System of the Swine Inverted Lymph Node ». Frontiers in Immunology 13 (2022): 869384. https://doi.org/10.3389/fimmu.2022.869384.
• Egbebike, Jennifer, Qi Shen, Kevin Doyle, Caroline A. Der-Nigoghossian, Lucy Panicker, Ian Jerome Gonzales, Lauren Grobois, et al. « Cognitive-Motor Dissociation and Time to Functional Recovery in Patients with Acute Brain Injury in the USA: A Prospective Observational Cohort Study ». The Lancet. Neurology 21, n^o 8 (août 2022): 704‑13. https://doi.org/10.1016/S1474-4422(22)00212-5.
• Ellul, Pierre, Eric Acquaviva, Hugo Peyre, Michelle Rosenzwajg, Pierre Gressens, David Klatzmann, et Richard Delorme. « Parental Autoimmune and Autoinflammatory Disorders as Multiple Risk Factors for Common Neurodevelopmental Disorders in Offspring: A Systematic Review and Meta-Analysis ». Translational Psychiatry 12, n^o 1 (18 mars 2022): 112. https://doi.org/10.1038/s41398-022-01843-y.
• Epelbaum, Stéphane, Ninon Burgos, Michael Canney, Dawn Matthews, Marion Houot, Mathieu D. Santin, Carole Desseaux, et al. « Pilot Study of Repeated Blood-Brain Barrier Disruption in Patients with Mild Alzheimer’s Disease with an Implantable Ultrasound Device ». Alzheimer’s Research & Therapy 14, n^o 1 (8 mars 2022): 40. https://doi.org/10.1186/s13195-022-00981-1.
• Faouzi, Johann, Samir Bekadar, Fanny Artaud, Alexis Elbaz, Graziella Mangone, Olivier Colliot, et Jean-Christophe Corvol. « Machine Learning-Based Prediction of Impulse Control Disorders in Parkinson’s Disease From Clinical and Genetic Data ». IEEE Open Journal of Engineering in Medicine and Biology 3 (2022): 96‑107. https://doi.org/10.1109/OJEMB.2022.3178295.
• Farcy, Sarah, Alexandra Albert, Pierre Gressens, Alexandre D. Baffet, et Vincent El Ghouzzi. « Cortical Organoids to Model Microcephaly ». Cells 11, n^o 14 (7 juillet 2022): 2135. https://doi.org/10.3390/cells11142135.
• Farooq, Muhammad, Mélanie Simoes Eugénio, Claire Piquet-Pellorce, Sarah Dion, Céline Raguenes-Nicol, Kathleen Santamaria, Ghania Hounana Kara-Ali, et al. « Receptor-Interacting Protein Kinase-1 Ablation in Liver Parenchymal Cells Promotes Liver Fibrosis in Murine NASH without Affecting Other Symptoms ». Journal of Molecular Medicine (Berlin, Germany) 100, n^o 7 (juillet 2022): 1027‑38. https://doi.org/10.1007/s00109-022-02192-5.
• Favrais, Geraldine, Cindy Bokobza, Elie Saliba, Sylvie Chalon, et Pierre Gressens. « Alteration of the Oligodendrocyte Lineage Varies According to the Systemic Inflammatory Stimulus in Animal Models That Mimic the Encephalopathy of Prematurity ». Frontiers in Physiology 13 (2022): 881674. https://doi.org/10.3389/fphys.2022.881674.
• Festari, Cristina, Federico Massa, Matteo Cotta Ramusino, Federica Gandolfo, Valentina Nicolosi, Stefania Orini, Dag Aarsland, et al. « European Consensus for the Diagnosis of MCI and Mild Dementia: Preparatory Phase ». Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 9 octobre 2022. https://doi.org/10.1002/alz.12798.
• Fevga, Christina, Christelle Tesson, Ana Carreras Mascaro, Thomas Courtin, Riaan van Coller, Salma Sakka, Federico Ferraro, et al. « PTPA Variants and Impaired PP2A Activity in Early-Onset Parkinsonism with Intellectual Disability ». Brain: A Journal of Neurology, 8 septembre 2022, awac326. https://doi.org/10.1093/brain/awac326.
• Finger, Elizabeth, Rubina Malik, Martina Bocchetta, Kristy Coleman, Caroline Graff, Barbara Borroni, Mario Masellis, et al. « Neurodevelopmental Effects of Genetic Frontotemporal Dementia in Young Adult Mutation Carriers ». Brain: A Journal of Neurology, 2 décembre 2022, awac446. https://doi.org/10.1093/brain/awac446.
• Foster, Phoebe H., Lucy L. Russell, Georgia Peakman, Rhian S. Convery, Arabella Bouzigues, Caroline V. Greaves, Martina Bocchetta, et al. « Examining Empathy Deficits across Familial Forms of Frontotemporal Dementia within the GENFI Cohort ». Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 150 (mai 2022): 12‑28. https://doi.org/10.1016/j.cortex.2022.01.012.
• Galea, Elena, Laura D. Weinstock, Raquel Larramona-Arcas, Alyssa F. Pybus, Lydia Giménez-Llort, Carole Escartin, et Levi B. Wood. « Multi-Transcriptomic Analysis Points to Early Organelle Dysfunction in Human Astrocytes in Alzheimer’s Disease ». Neurobiology of Disease 166 (mai 2022): 105655. https://doi.org/10.1016/j.nbd.2022.105655.
• Gallezot, Charlotte, Rachid Riad, Hadrien Titeux, Laurie Lemoine, Justine Montillot, Agnes Sliwinski, Jennifer Hamet Bagnou, et al. « Emotion Expression through Spoken Language in Huntington Disease ». Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 155 (octobre 2022): 150‑61. https://doi.org/10.1016/j.cortex.2022.05.024.
• Gallou-Guyot, M., D. Nuic, S. Mandigout, M. Compagnat, M. L. Welter, J. C. Daviet, et A. Perrochon. « Effectiveness of Home-Based Rehabilitation Using Active Video Games on Quality of Life, Cognitive and Motor Functions in People with Parkinson’s Disease: A Systematic Review ». Disability and Rehabilitation 44, n^o 26 (décembre 2022): 8222‑33. https://doi.org/10.1080/09638288.2021.2022780.
• Garin, Clément M., Yuki Hori, Stefan Everling, Christopher T. Whitlow, Finnegan J. Calabro, Beatriz Luna, Mathilda Froesel, et al. « An Evolutionary Gap in Primate Default Mode Network Organization ». Cell Reports 39, n^o 2 (12 avril 2022): 110669. https://doi.org/10.1016/j.celrep.2022.110669.
• Garin, Clément M., Nachiket A. Nadkarni, Jérémy Pépin, Julien Flament, et Marc Dhenain. « Whole Brain Mapping of Glutamate Distribution in Adult and Old Primates at 11.7T ». NeuroImage 251 (1 mai 2022): 118984. https://doi.org/10.1016/j.neuroimage.2022.118984.
• Garrel, Ghislaine, Claude Rouch, David L’Hôte, Salma Tazi, Nadim Kassis, Frank Giton, Julien Dairou, et al. « Disruption of Pituitary Gonadotrope Activity in Male Rats After Short- or Long-Term High-Fat Diets Is Not Associated With Pituitary Inflammation ». Frontiers in Endocrinology 13 (2022): 877999. https://doi.org/10.3389/fendo.2022.877999.
• Gaurav, Rahul, Romain Valabrègue, Lydia Yahia-Chérif, Graziella Mangone, Sridar Narayanan, Isabelle Arnulf, Marie Vidailhet, Jean-Christophe Corvol, et Stéphane Lehéricy. « NigraNet: An Automatic Framework to Assess Nigral Neuromelanin Content in Early Parkinson’s Disease Using Convolutional Neural Network ». NeuroImage. Clinical 36 (2022): 103250. https://doi.org/10.1016/j.nicl.2022.103250.
• Gavoille, Antoine, Fabien Rollot, Romain Casey, Marc Debouverie, Emmanuelle Le Page, Jonathan Ciron, Jerome De Seze, et al. « Investigating the Long-Term Effect of Pregnancy on the Course of Multiple Sclerosis Using Causal Inference ». Neurology, 23 décembre 2022, 10.1212/WNL.0000000000206774. https://doi.org/10.1212/WNL.0000000000206774.
• Gazzina, Stefano, Mario Grassi, Enrico Premi, Antonella Alberici, Alberto Benussi, Silvana Archetti, Roberto Gasparotti, et al. « Structural Brain Splitting Is a Hallmark of Granulin-Related Frontotemporal Dementia ». Neurobiology of Aging 114 (juin 2022): 94‑104. https://doi.org/10.1016/j.neurobiolaging.2022.02.009.
• Gendre, T., Ovaska H., Nguyen R., Bachoud-Levi AC., Khellaf M., et Remy P. « New diagnostic challenge at the Emergency Room: Acute ataxia induced by nitrous oxide abuse in young adults during the COVID-19 outbreak ». Emergencia, 2022.
• Gilvesy, Abris, Evelina Husen, Zsofia Magloczky, Orsolya Mihaly, Tibor Hortobágyi, Shigeaki Kanatani, Helmut Heinsen, et al. « Spatiotemporal Characterization of Cellular Tau Pathology in the Human Locus Coeruleus-Pericoerulear Complex by Three-Dimensional Imaging ». Acta Neuropathologica 144, n^o 4 (octobre 2022): 651‑76. https://doi.org/10.1007/s00401-022-02477-6.
• Glasman, Pauline, Marion Houot, Raffaela Migliaccio, Stéphanie Bombois, Geoffroy Gagliardi, Federica Cacciamani, Marie Odile Habert, Bruno Dubois, Stéphane Epelbaum, et INSIGHT-PreAD study group. « Subtle Postoperative Cognitive Disorder in Preclinical Alzheimer’s Disease ». Experimental Gerontology 161 (mai 2022): 111715. https://doi.org/10.1016/j.exger.2022.111715.
• Godefroy, Valérie, Bénédicte Batrancourt, Sylvain Charron, Arabella Bouzigues, David Bendetowicz, Guilhem Carle, Armelle Rametti-Lacroux, et al. « Functional Connectivity Correlates of Reduced Goal-Directed Behaviors in Behavioural Variant Frontotemporal Dementia ». Brain Structure & Function 227, n^o 9 (décembre 2022): 2971‑89. https://doi.org/10.1007/s00429-022-02519-5.
• Godefroy, Valérie, Bénédicte Batrancourt, Sylvain Charron, Arabella Bouzigues, Idil Sezer, David Bendetowicz, Guilhem Carle, et al. « Disentangling Clinical Profiles of Apathy in Behavioral Variant Frontotemporal Dementia ». Journal of Alzheimer’s Disease: JAD 90, n^o 2 (2022): 639‑54. https://doi.org/10.3233/JAD-220370.
• Gougeon, Eliot, Thibaut Larcher, Mireille Ledevin, Yvonne McGrotty, et Pierre Méheust. « Myopathy with Oval Inclusions in a Domestic Shorthair Cat ». JFMS Open Reports 8, n^o 1 (2022): 20551169221081416. https://doi.org/10.1177/20551169221081418.
• Gressens, Pierre. « Extracellular Vesicles at the Rescue of the Preterm Brain ». Brain, Behavior, and Immunity 102 (mai 2022): 135‑36. https://doi.org/10.1016/j.bbi.2022.02.014.
• Grover, Sandeep, Ashwin Ashok Kumar Sreelatha, Lasse Pihlstrom, Cloé Domenighetti, Claudia Schulte, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, et al. « Genome-Wide Association and Meta-Analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium ». Neurology 99, n^o 7 (16 août 2022): e698‑710. https://doi.org/10.1212/WNL.0000000000200699.
• Hanbouch, Linda, Béatrice Schaack, Amal Kasri, Gaëlle Fontaine, Eleni Gkanatsiou, Gunnar Brinkmalm, Elena Camporesi, et al. « Specific Mutations in the Cholesterol-Binding Site of APP Alter Its Processing and Favor the Production of Shorter, Less Toxic Aβ Peptides ». Molecular Neurobiology 59, n^o 11 (novembre 2022): 7056‑73. https://doi.org/10.1007/s12035-022-03025-9.
• Hare, Emily, Anne-Catherine Bachoud-Lévi, Ralf Reilmann, David Craufurd, Monica Busse, Anne Rosser, et Duncan McLauchlan. « Cognitive Processes of Apathy in Huntington’s Disease Show High Sensitivity to Disease Progression ». Clinical Parkinsonism & Related Disorders 7 (2022): 100168. https://doi.org/10.1016/j.prdoa.2022.100168.
• Hurk, Mark van den, Shong Lau, Maria C. Marchetto, Jerome Mertens, Shani Stern, Olga Corti, Alexis Brice, et al. « Druggable Transcriptomic Pathways Revealed in Parkinson’s Patient-Derived Midbrain Neurons ». NPJ Parkinson’s Disease 8, n^o 1 (18 octobre 2022): 134. https://doi.org/10.1038/s41531-022-00400-0.
• Iannielli, Angelo, Mirko Luoni, Serena Gea Giannelli, Rosangela Ferese, Gabriele Ordazzo, Matteo Fossati, Andrea Raimondi, et al. « Modeling Native and Seeded Synuclein Aggregation and Related Cellular Dysfunctions in Dopaminergic Neurons Derived by a New Set of Isogenic IPSC Lines with SNCA Multiplications ». Cell Death & Disease 13, n^o 10 (19 octobre 2022): 881. https://doi.org/10.1038/s41419-022-05330-6.
• Jacob, Laurent, Jose de Brito Neto, Stephanie Lenck, Celine Corcy, Farhat Benbelkacem, Luiz Henrique Geraldo, Yunling Xu, et al. « Conserved Meningeal Lymphatic Drainage Circuits in Mice and Humans ». The Journal of Experimental Medicine 219, n^o 8 (1 août 2022): e20220035. https://doi.org/10.1084/jem.20220035.
• Jacquens, Alice, Edward J. Needham, Elisa R. Zanier, Vincent Degos, Pierre Gressens, et David Menon. « Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side ». International Journal of Molecular Sciences 23, n^o 19 (23 septembre 2022): 11193. https://doi.org/10.3390/ijms231911193.
• Jansen, Willemijn J., Olin Janssen, Betty M. Tijms, Stephanie J. B. Vos, Rik Ossenkoppele, Pieter Jelle Visser, Amyloid Biomarker Study Group, et al. « Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum ». JAMA Neurology 79, n^o 3 (1 mars 2022): 228‑43. https://doi.org/10.1001/jamaneurol.2021.5216.
• Jeancolas, Laetitia, Graziella Mangone, Dijana Petrovska-Delacrétaz, Habib Benali, Badr-Eddine Benkelfat, Isabelle Arnulf, Jean-Christophe Corvol, Marie Vidailhet, et Stéphane Lehéricy. « Voice Characteristics from Isolated Rapid Eye Movement Sleep Behavior Disorder to Early Parkinson’s Disease ». Parkinsonism & Related Disorders 95 (février 2022): 86‑91. https://doi.org/10.1016/j.parkreldis.2022.01.003.
• Kaivola, Karri, Zalak Shah, Ruth Chia, International LBD Genomics Consortium, et Sonja W. Scholz. « Genetic Evaluation of Dementia with Lewy Bodies Implicates Distinct Disease Subgroups ». Brain: A Journal of Neurology 145, n^o 5 (3 juin 2022): 1757‑62. https://doi.org/10.1093/brain/awab402.
• Khayenko, Vladimir, Clemens Schulte, Sara L. Reis, Orly Avraham, Cataldo Schietroma, Rafael Worschech, Noah F. Nordblom, et al. « A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity ». Angewandte Chemie (International Ed. in English) 61, n^o 30 (25 juillet 2022): e202202078. https://doi.org/10.1002/anie.202202078.
• Khedher, Laila, Jean-Marie Bonny, Ana Marques, Elodie Durand, Bruno Pereira, Marie Chupin, Tiphaine Vidal, et al. « Intrasubject Subcortical Quantitative Referencing to Boost MRI Sensitivity to Parkinson’s Disease ». NeuroImage. Clinical 36 (2022): 103231. https://doi.org/10.1016/j.nicl.2022.103231.
• Klein, Luisa, Juliette Van Steenwinckel, Bobbi Fleiss, Till Scheuer, Christoph Bührer, Valerie Faivre, Sophie Lemoine, et al. « A Unique Cerebellar Pattern of Microglia Activation in a Mouse Model of Encephalopathy of Prematurity ». Glia 70, n^o 9 (septembre 2022): 1699‑1719. https://doi.org/10.1002/glia.24190.
• Kliest, Tessa, Ruben P. A. Van Eijk, Ammar Al-Chalabi, Alberto Albanese, Peter M. Andersen, Maria Del Mar Amador, Geir BrÅthen, et al. « Clinical Trials in Pediatric ALS: A TRICALS Feasibility Study ». Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 23, n^o 7‑8 (novembre 2022): 481‑88. https://doi.org/10.1080/21678421.2021.2024856.
• Kmetzsch, Virgilio, Morwena Latouche, Dario Saracino, Daisy Rinaldi, Agnès Camuzat, Thomas Gareau, French Research Network on FTD/ALS, Isabelle Le Ber, Olivier Colliot, et Emmanuelle Becker. « MicroRNA Signatures in Genetic Frontotemporal Dementia and Amyotrophic Lateral Sclerosis ». Annals of Clinical and Translational Neurology 9, n^o 11 (novembre 2022): 1778‑91. https://doi.org/10.1002/acn3.51674.
• Kossorotoff, Manoëlle, Basile Kerleroux, Grégoire Boulouis, Béatrice Husson, Kim Tran Dong, François Eugene, Lena Damaj, et al. « Recanalization Treatments for Pediatric Acute Ischemic Stroke in France ». JAMA Network Open 5, n^o 9 (1 septembre 2022): e2231343. https://doi.org/10.1001/jamanetworkopen.2022.31343.
• Koukouli, Fani, Martin Montmerle, Andrea Aguirre, Marcel De Brito Van Velze, Jérémy Peixoto, Vikash Choudhary, Marjorie Varilh, et al. « Visual-Area-Specific Tonic Modulation of GABA Release by Endocannabinoids Sets the Activity and Coordination of Neocortical Principal Neurons ». Cell Reports 40, n^o 8 (23 août 2022): 111202. https://doi.org/10.1016/j.celrep.2022.111202.
• Koutsouleris, Nikolaos, Christos Pantelis, Dennis Velakoulis, Philip McGuire, Dominic B. Dwyer, Maria-Fernanda Urquijo-Castro, Riya Paul, et al. « Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited ». JAMA Psychiatry 79, n^o 9 (1 septembre 2022): 907‑19. https://doi.org/10.1001/jamapsychiatry.2022.2075.
• Koval, Igor, Thomas Dighiero-Brecht, Allan J. Tobin, Sarah J. Tabrizi, Rachael I. Scahill, Sophie Tezenas du Montcel, Stanley Durrleman, et Alexandra Durr. « Forecasting Individual Progression Trajectories in Huntington Disease Enables More Powered Clinical Trials ». Scientific Reports 12, n^o 1 (7 novembre 2022): 18928. https://doi.org/10.1038/s41598-022-18848-8.
• Lam, Suzanne, Anne-Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, Brainbank Neuro-CEB Neuropathology Network, et al. « Pathological Changes Induced by Alzheimer’s Brain Inoculation in Amyloid-Beta Plaque-Bearing Mice ». Acta Neuropathologica Communications 10, n^o 1 (16 août 2022): 112. https://doi.org/10.1186/s40478-022-01410-y.
• Landau, Anne M., Nadja Van Camp, et Alexandra Petiet. « Editorial: Advanced Imaging Techniques and Imaging Markers of Synaptic Density and Brain Connectivity in Animal Models of Neurological Diseases ». Frontiers in Neuroscience 16 (2022): 980368. https://doi.org/10.3389/fnins.2022.980368.
• Lang, Anthony E., Andrew D. Siderowf, Eric A. Macklin, Werner Poewe, David J. Brooks, Hubert H. Fernandez, Olivier Rascol, et al. « Trial of Cinpanemab in Early Parkinson’s Disease ». The New England Journal of Medicine 387, n^o 5 (4 août 2022): 408‑20. https://doi.org/10.1056/NEJMoa2203395.
• Lanore, Aymeric, Suzanne Lesage, Louise-Laure Mariani, Poornima Jayadev Menon, Philippe Ravassard, Helene Cheval, Olga Corti, Alexis Brice, et Jean-Christophe Corvol. « Does the Expression and Epigenetics of Genes Involved in Monogenic Forms of Parkinson’s Disease Influence Sporadic Forms? » Genes 13, n^o 3 (8 mars 2022): 479. https://doi.org/10.3390/genes13030479.
• Lantier, Isabelle, Corentin Mallet, Laurent Souci, Thibaut Larcher, Andele M. Conradie, Katia Courvoisier, Sascha Trapp, David Pasdeloup, Benedikt B. Kaufer, et Caroline Denesvre. « In Vivo Imaging Reveals Novel Replication Sites of a Highly Oncogenic Avian Herpesvirus in Chickens ». PLoS Pathogens 18, n^o 8 (août 2022): e1010745. https://doi.org/10.1371/journal.ppat.1010745.
• Lazar, Adina-Nicoleta, Linda Hanbouch, Lydie Boussicaut, Baptiste Fourmaux, Patricia Daira, Mark J. Millan, Nathalie Bernoud-Hubac, et Marie-Claude Potier. « Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology ». Cells 11, n^o 22 (15 novembre 2022): 3616. https://doi.org/10.3390/cells11223616.
• Lazarini, Françoise, Sarah Levivien, Yoann Madec, Fabien Taieb, Estelle Mottez, Tan-Phuc Buivan, Audrey Maudoux, et al. « Olfactory Function in Congenital Cytomegalovirus Infection: A Prospective Study ». European Journal of Pediatrics 181, n^o 5 (mai 2022): 1859‑69. https://doi.org/10.1007/s00431-022-04375-1.
• Lazzarotto, Andrea, Matteo Tonietto, Emilie Poirion, Marco Battaglini, Raffaele Palladino, Charline Benoit, Vito Ag Ricigliano, et al. « Clinically Relevant Profiles of Myelin Content Changes in Patients with Multiple Sclerosis: A Multimodal and Multicompartment Imaging Study ». Multiple Sclerosis (Houndmills, Basingstoke, England) 28, n^o 12 (octobre 2022): 1881‑90. https://doi.org/10.1177/13524585221096975.
• Lefort, M., S. Sharmin, J. B. Andersen, S. Vukusic, R. Casey, M. Debouverie, G. Edan, et al. « Impact of Methodological Choices in Comparative Effectiveness Studies: Application in Natalizumab versus Fingolimod Comparison among Patients with Multiple Sclerosis ». BMC Medical Research Methodology 22, n^o 1 (30 mai 2022): 155. https://doi.org/10.1186/s12874-022-01623-8.
• Lefort, Mathilde, Sandra Vukusic, Romain Casey, Gilles Edan, Emmanuelle Leray, et OFSEP investigators. « Disability Progression in Multiple Sclerosis Patients Using Early First-Line Treatments ». European Journal of Neurology 29, n^o 9 (26 mai 2022): 2761‑71. https://doi.org/10.1111/ene.15422.
• Lespinasse, Jérémie, Geneviève Chêne, Jean-Francois Mangin, Bruno Dubois, Frederic Blanc, Claire Paquet, Olivier Hanon, et al. « Associations among Hypertension, Dementia Biomarkers, and Cognition: The MEMENTO Cohort ». Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 4 décembre 2022. https://doi.org/10.1002/alz.12866.
• Levy, Marion J. F., Beatriz Garcia-Diaz, Frédéric Sedel, Anne Baron-Van Evercooren, et Sabah Mozafari. « High Dose Pharmaceutical Grade Biotin (MD1003) Accelerates Differentiation of Murine and Grafted Human Oligodendrocyte Progenitor Cells In Vivo ». International Journal of Molecular Sciences 23, n^o 24 (12 décembre 2022): 15733. https://doi.org/10.3390/ijms232415733.
• Leyrolle, Quentin, Fanny Decoeur, Cyril Dejean, Galadriel Brière, Stephane Leon, Ioannis Bakoyiannis, Emilie Baroux, et al. « N-3 PUFA Deficiency Disrupts Oligodendrocyte Maturation and Myelin Integrity during Brain Development ». Glia 70, n^o 1 (janvier 2022): 50‑70. https://doi.org/10.1002/glia.24088.
• Liu, Changliang, Rui Gao, Yidan Tang, Hai Chen, Xueying Zhang, Yalan Sun, Qi Zhao, et al. « Identification of Potential Key Circular RNAs Related to Cognitive Impairment after Chronic Constriction Injury of the Sciatic Nerve ». Frontiers in Neuroscience 16 (2022): 925300. https://doi.org/10.3389/fnins.2022.925300.
• Liu, Shu-Ying, Hong-Wen Qiao, Tian-Bin Song, Xiu-Lin Liu, Yun-Xia Yao, Chun-Song Zhao, Olivier Barret, et al. « Brain Microglia Activation and Peripheral Adaptive Immunity in Parkinson’s Disease: A Multimodal PET Study ». Journal of Neuroinflammation 19, n^o 1 (29 août 2022): 209. https://doi.org/10.1186/s12974-022-02574-z.
• Liu, Xiu-Lin, Shu-Ying Liu, Olivier Barret, Gilles D. Tamagnan, Hong-Wen Qiao, Tian-Bin Song, Jie Lu, et Piu Chan. « Diagnostic Value of Striatal 18F-FP-DTBZ PET in Parkinson’s Disease ». Frontiers in Aging Neuroscience 14 (2022): 931015. https://doi.org/10.3389/fnagi.2022.931015.
• Löhle, Matthias, Graziella Mangone, Wiebke Hermann, Denise Hausbrand, Martin Wolz, Julia Mende, Heinz Reichmann, Andreas Hermann, Jean-Christophe Corvol, et Alexander Storch. « Functional MAOB Gene Intron 13 Polymorphism Predicts Dyskinesia in Parkinson’s Disease ». Parkinson’s Disease 2022 (2022): 5597503. https://doi.org/10.1155/2022/5597503.
• Louapre, Céline, Bruno Stankoff, et Benedetta Bodini. « [Multiple sclerosis: what therapeutic perspectives ?] ». La Revue Du Praticien 72, n^o 4 (avril 2022): 410‑15.